chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Base Information

Chemical Name:chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate
CAS No.:872329-48-1
Molecular Formula:C₁₉H₁₇ClN₄O₃
Molecular Weight:384.822
Hs Code.:

Synonyms:chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Suppliers and Price of chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

There total 4 articles about chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 872329-95-8
1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylic acid

: 49715-04-0
chlorosulfuric acid chloromethyl ester

: 872329-48-1
chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Guidance literature:: tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; In dichloromethane; water; at 0 - 20 ℃; for 5.5h;

Reference yield:

: ethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

: 872329-48-1
chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide; ethanol; water / 4 h / 60 °C

1.2: pH 2

2.1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate / dichloromethane; water / 5.5 h / 0 - 20 °C

With sodium hydroxide; ethanol; water; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 872329-48-1
chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine / 1,4-dioxane / 48 h / 130 °C

2.1: sodium hydroxide; ethanol; water / 4 h / 60 °C

2.2: pH 2

3.1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate / dichloromethane; water / 5.5 h / 0 - 20 °C

With sodium hydroxide; copper(l) iodide; ethanol; water; potassium carbonate; N,N`-dimethylethylenediamine; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; In 1,4-dioxane; dichloromethane; water;