3-Aminomethylphenylboronicacidpinacolester

Base Information

Chemical Name:3-Aminomethylphenylboronicacidpinacolester
CAS No.:269410-09-5
Molecular Formula:C13H20 B N O2
Molecular Weight:233.118
Hs Code.:
Mol file:269410-09-5.mol

Synonyms:3-Aminomethylphenylboronicacidpinacolester

Suppliers and Price of 3-Aminomethylphenylboronicacidpinacolester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of 3-Aminomethylphenylboronicacidpinacolester

Chemical Property:

PSA：44.48000
LogP:2.14480

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Aminomethylphenylboronicacidpinacolester

There total 9 articles about 3-Aminomethylphenylboronicacidpinacolester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.6%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: [3-(aminomethyl)phenyl]boronic acid

: 269410-09-5
(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine

Guidance literature:: In toluene; for 2h; Dean-Stark; Reflux; Inert atmosphere;
DOI:10.1021/ol402271a

Reference yield: 82.0%

: 214360-75-5
2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]isoindoline-1,3-dione

: 269410-09-5
(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine

Guidance literature:: With hydrazine hydrate; In tetrahydrofuran; for 12h; Reflux;
DOI:10.3390/molecules181012346

Reference yield:

: 87199-16-4
3-Formylphenylboronic acid

: 269410-09-5
(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine

Guidance literature:: Multi-step reaction with 5 steps

1: magnesium sulfate / methanol / 6 h / 20 °C

2: sodium tetrahydroborate / 5 h / 20 °C

3: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 0 °C / Inert atmosphere

4: potassium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C

5: hydrazine hydrate / tetrahydrofuran / 12 h / Reflux

With sodium tetrahydroborate; magnesium sulfate; potassium carbonate; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.3390/molecules181012346