(1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

Base Information

Chemical Name:(1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane
CAS No.:128329-40-8
Molecular Formula:C₃₃H₅₃IO₄Si₂
Molecular Weight:696.857
Hs Code.:

Synonyms:(1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

Suppliers and Price of (1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

There total 2 articles about (1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 128358-15-6
(1''R,2'R,4S,5'S)-4-<<(diphenylisopropoxy)silyl>oxy>-4-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>-1-pentanol

: 128329-40-8
(1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

Guidance literature:: With 1H-imidazole; iodine; triphenylphosphine; In tetrahydrofuran; acetonitrile; for 4h; Ambient temperature;
DOI:10.1021/ja00169a041

Reference yield:

: 128329-39-5,128443-27-6
Acetic acid 4-{(2R,5S)-5-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-5-methyl-tetrahydro-furan-2-yl}-4-(isopropoxy-diphenyl-silanyloxy)-pentyl ester

: 128329-40-8
(1''R,2S,2'R,5'S)-2-<<(diphenylisopropoxy)silyl>oxy>-5-iodo-2-<5'-<1''-<(tert-butyldimethylsilyl)oxy>ethyl>-2',3',4',5'-tetrahydro-5'-methylfuran-2'-yl>pentane

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / lithium aluminum hydride / diethyl ether / 0.33 h / -25 °C

2: 91 percent / triphenylphosphine, imidazole, iodine / tetrahydrofuran; acetonitrile / 4 h / Ambient temperature

With 1H-imidazole; lithium aluminium tetrahydride; iodine; triphenylphosphine; In tetrahydrofuran; diethyl ether; acetonitrile;
DOI:10.1021/ja00169a041