Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate

Base Information

Chemical Name:Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate
CAS No.:910541-11-6
Molecular Formula:C₂₇H₂₈N₂O₄
Molecular Weight:444.53
Hs Code.:
ChEMBL ID:CHEMBL1531411
DSSTox Substance ID:DTXSID501114235

Synonyms:MLS000877839;CHEMBL1531411;DTXSID501114235;HMS2219L15;UPCMLD04BGHW001004:001;NCGC00165427-01;910541-11-6;Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate;SMR000472100

Suppliers and Price of Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:444.20490738
Heavy Atom Count:33
Complexity:624

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)NC(C3=CC=CC=C3)C(C4=CC=CC=C4)O
Isomeric SMILES:C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C(=O)N[C@@H](C3=CC=CC=C3)[C@@H](C4=CC=CC=C4)O

Technology Process of Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate

There total 3 articles about Phenylmethyl (2S)-2-[[[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino]carbonyl]-1-pyrrolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23190-16-1
(1R,2S)-2-Amino-1,2-diphenylethanol

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 910541-11-6
(S)-2-((1S,2R)-2-Hydroxy-1,2-diphenyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: N-Benzyloxycarbonyl-L-proline; With TEA; chloroformic acid ethyl ester; In tetrahydrofuran; at 0 ℃;

(1R,2S)-2-Amino-1,2-diphenylethanol; In tetrahydrofuran;
DOI:10.1021/ja034528q

Reference yield:

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 910541-11-6
(S)-2-((1S,2R)-2-Hydroxy-1,2-diphenyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: TEA / tetrahydrofuran

2: tetrahydrofuran

With TEA; In tetrahydrofuran;
DOI:10.1016/j.tetasy.2006.07.023