(1R,2S)-(-)-2-Amino-1,2-diphenylethanol

Base Information

Chemical Name:(1R,2S)-(-)-2-Amino-1,2-diphenylethanol
CAS No.:23190-16-1
Molecular Formula:C14H15NO
Molecular Weight:213.279
Hs Code.:29221990
European Community (EC) Number:627-453-2
Nikkaji Number:J373.765I
ChEMBL ID:CHEMBL442934
Mol file:23190-16-1.mol

Synonyms:2-amino-1,2-diphenylethanol;erythro-2-amino-1,2-diphenylethanol

Suppliers and Price of (1R,2S)-(-)-2-Amino-1,2-diphenylethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1R,2S)-(-)-2-Amino-1,2-diphenylethanol
25g
$ 625.00

TRC
(1R,2S)-(-)-2-Amino-1,2-diphenylethanol
1g
$ 50.00

TCI Chemical
(1R,2S)-(-)-2-Amino-1,2-diphenylethanol >99.0%(GC)(T)
1g
$ 19.00

TCI Chemical
(1R,2S)-(-)-2-Amino-1,2-diphenylethanol >99.0%(GC)(T)
5g
$ 53.00

SynQuest Laboratories
(1R,2S)-2-Amino-1,2-diphenylethan-1-ol
1 g
$ 55.00

SynQuest Laboratories
(1R,2S)-2-Amino-1,2-diphenylethan-1-ol
250 mg
$ 25.00

SynQuest Laboratories
(1R,2S)-2-Amino-1,2-diphenylethan-1-ol
5 g
$ 95.00

Strem Chemicals
(1R,2S)-2-Amino-1,2-diphenylethanol, min. 98%
25g
$ 398.00

Strem Chemicals
(1R,2S)-2-Amino-1,2-diphenylethanol, min. 98%
5g
$ 100.00

Sigma-Aldrich
(1R,2S)-(?)-2-Amino-1,2-diphenylethanol 99%
5g
$ 93.80

Total 151 raw suppliers

Chemical Property of (1R,2S)-(-)-2-Amino-1,2-diphenylethanol

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:2.88E-06mmHg at 25°C
Melting Point:142-144 °C(lit.)
Refractive Index:-7 ° (C=0.6, EtOH)
Boiling Point:261 °C at 760 mmHg
PKA:11.70±0.45(Predicted)
Flash Point:125.3 °C
PSA：46.25000
Density:1.148 g/cm₃
LogP:3.12030
Storage Temp.:2-8°C
Solubility.:Chloroform, Ethanol, Methanol
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:213.115364102
Heavy Atom Count:16
Complexity:195

Purity/Quality:

99% min ^*data from raw suppliers

(1R,2S)-(-)-2-Amino-1,2-diphenylethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(C2=CC=CC=C2)O)N
Isomeric SMILES:C1=CC=C(C=C1)[C@@H]([C@@H](C2=CC=CC=C2)O)N
Uses (1R,2S)-(-)-2-Amino-1,2-diphenylethanol is a hydroxylated 1,2-diphenethylamine derivative with affinity for the NMDA receptor. Chiral auxiliary used for Pd(II)-assisted chiral tandem alkylation and carbonylative coupling reactions.

Technology Process of (1R,2S)-(-)-2-Amino-1,2-diphenylethanol

There total 214 articles about (1R,2S)-(-)-2-Amino-1,2-diphenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 133522-22-2
(1R,2S)-2-azido-1,2-diphenylethan-1-ol

: 23190-16-1
(1R,2S)-2-Amino-1,2-diphenylethanol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 12h; atmospheric pressure;
DOI:10.1021/jo034133p

Reference yield: 88.0%

: 301191-47-9
N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide

: 23190-16-1
(1R,2S)-2-Amino-1,2-diphenylethanol

Guidance literature:: N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide; With thionyl chloride; at -15 - 20 ℃;

With water; for 3h; Heating;
DOI:10.1016/S0040-4020(00)00481-6