5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

Base Information

• Chemical Name: 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide
• CAS No.: 247568-44-1
• Molecular Formula: C₂₀H₂₂N₄O₅
• Molecular Weight: 398.418
• Mol file: 247568-44-1.mol

Synonyms:5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

Chemical Property of 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

There total 82 articles about 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Cyanobenzyl alcohol (874-89-5) → 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247568-44-1)

Guidance literature:

Multi-step reaction with 6 steps

3: hydrazine hydrate / ethanol

6: trifluoroacetic acid / dichloromethane

With hydrazine hydrate; trifluoroacetic acid; In ethanol; dichloromethane;

Reference yield:

2-[1-(tert-butoxycarbonyl)-4-piperidinylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247568-43-0) → 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247568-44-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

Reference yield:

2-(cyclopentylamino)-5-nitrobenzoic acid (247568-48-5) → 5-nitro-2-(4-piperidinylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247568-44-1)

Guidance literature:

Multi-step reaction with 3 steps

3: trifluoroacetic acid / dichloromethane

With trifluoroacetic acid; In dichloromethane;

upstream raw materials:

2-[1-(tert-butoxycarbonyl)-4-piperidinylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide

3-methoxy-4-(2-methoxyethoxy)benzonitrile

2-(cyclopentylamino)-5-nitrobenzoic acid

benzofuran-2-carbonitrile

Downstream raw materials:

2-(1-methyl-4-piperidinylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide

2-(1-Formyl-4-piperidinylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide