(9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Base Information

Chemical Name:(9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide
CAS No.:714217-39-7
Molecular Formula:C₃₀H₄₆O₆
Molecular Weight:502.692
Hs Code.:

Synonyms:(9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Suppliers and Price of (9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

There total 5 articles about (9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 714217-38-6
8,8a-deoxa-3,5-O-(2,4,6-trimethylbenzylidene)-oleandonolide

: 714217-39-7
(9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Guidance literature:: With sodium tetrahydroborate; cerium(III) chloride; In tetrahydrofuran; at -25 ℃; for 4.5h;
DOI:10.1016/j.tet.2004.03.061

Reference yield:

: 64761-29-1
mesitaldehyde dimethylacetal

: 714217-39-7
(9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Guidance literature:: Multi-step reaction with 4 steps

1: 57 percent / camphorsulfonic acid / CH₂Cl₂ / 6 h / 20 °C

2: 118 mg / aq. NaHCO₃ / tetrahydrofuran / 0.33 h / 0 °C

3: 64 percent / CrCl₂ / acetone; H₂O / 3 h / 0 °C

4: 91 percent / CeCl₃*H₂O; NaBH₄ / tetrahydrofuran / 4.5 h / -25 °C

With chromium dichloride; sodium tetrahydroborate; cerium(III) chloride; camphor-10-sulfonic acid; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water; acetone;
DOI:10.1016/j.tet.2004.03.061

Reference yield:

: 116417-70-0
(8S)-8,8a-deepoxy-8-hydroxy-8a-iodooleandonolide

: 714217-39-7
(9R)-3,5-O-(2,4,6-trimethylbenzylidene)-8,8a-deoxa-9-dihydro-oleandonolide

Guidance literature:: Multi-step reaction with 4 steps

1: 57 percent / camphorsulfonic acid / CH₂Cl₂ / 6 h / 20 °C

2: 118 mg / aq. NaHCO₃ / tetrahydrofuran / 0.33 h / 0 °C

3: 64 percent / CrCl₂ / acetone; H₂O / 3 h / 0 °C

4: 91 percent / CeCl₃*H₂O; NaBH₄ / tetrahydrofuran / 4.5 h / -25 °C

With chromium dichloride; sodium tetrahydroborate; cerium(III) chloride; camphor-10-sulfonic acid; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water; acetone;
DOI:10.1016/j.tet.2004.03.061