Technology Process of 5-fluoro-BAPTA tetramethyl ester
There total 3 articles about 5-fluoro-BAPTA tetramethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate; sodium iodide;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 21h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 19 h / 90 - 110 °C
2: acetic acid; palladium on activated charcoal / 1,4-dioxane / 20 °C
3: sodium iodide; potassium carbonate / N,N-dimethyl-formamide / 21 h / 80 °C
With
palladium on activated charcoal; potassium carbonate; acetic acid; sodium iodide;
In
1,4-dioxane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 110 - 120 °C
2: potassium carbonate / N,N-dimethyl-formamide / 19 h / 90 - 110 °C
3: acetic acid; palladium on activated charcoal / 1,4-dioxane / 20 °C
4: sodium iodide; potassium carbonate / N,N-dimethyl-formamide / 21 h / 80 °C
With
palladium on activated charcoal; potassium carbonate; acetic acid; sodium iodide;
In
1,4-dioxane; N,N-dimethyl-formamide;
