102236-25-9Relevant articles and documents
A Comprehensive Study of the Ca2+ Ion Binding of Fluorescently Labelled BAPTA Analogues
Csomos, Attila,Kontra, Bence,Jancsó, Attila,Galbács, Gábor,Deme, Ruth,Kele, Zoltán,Rózsa, Balázs József,Kovács, Ervin,Mucsi, Zoltán
supporting information, p. 5248 - 5261 (2021/10/19)
Since its development, the ionophore BAPTA (1,2-bis(2-aminophenoxy)-ethane-N,N,N’,N’-tetraacetic acid) has been used unchanged in calcium sensing applications. In this work we present a comprehensive experimental and theoretical study of novel alterations in the structure of BAPTA, with a focus on the systematic modification of the chain connecting the two aromatic rings of the molecule (denoted as “linker”). A bis-(diethylamino)xantene fluorophore was also attached to the structures in a fixed position and the structure-fluorescence response relationship of these molecules was investigated in addition. The effect of the linker's length, the number of oxygen atoms in this chain and even the removal of one of the rings was tested; these all proved to significantly alter the characteristics of the compounds. For example, it was found that the second aromatic ring of BAPTA is not essential for the turn-on of the fluorescence. We also demonstrated that successful sensing can be realized even by replacing the chain with a single oxygen atom, which suggests the availability of a new calcium binding mode of the chelator. The reliable turn-on characteristic, the steep Ca2+ fluorescence titration curve and the intense fluorescence emission combine to make this compound a prospective candidate as a calcium sensing molecular probe in diagnostic neurobiological applications.
METHODS FOR PREPARING FUEL ADDITIVES
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Page/Page column 34, (2019/07/17)
A method is provided for preparing a fuel additive having the formula: ( l ) The method comprises carrying out the following reactions: (i) addition of an alkylating agent b to starting material a: (a) to form an intermediate c; and (ii) ring closing intermediate c to form fuel additive e.
Structural study and fluorescent property of a novel organic microporous crystalline material
Cheng, Zhao,Yang, Bingqin,Yang, Meipan,Zhang, Binglin
, p. 112 - 118 (2014/02/14)
A novel microporous organic material [(2-{2-[2-(bis- methoxycarbonylmethylamino)phenoxy] ethoxy}-4-benzimidazole-phenyl) methoxycarbonylmethylamino]acetic acid methyl ester 6 was synthesized and characterized by single crystal X-ray diffraction, Fourier transform infrared spectroscopy (FT-IR), electron spray ionization-mass spectrometry (ESI-HRMS), X-ray powder diffraction (PXRD), 1H and 13C NMR. 6 crystallizes in the centrosymmetric monoclinic space group C2/c, with unit cell parameters a = 35.648(3) A?, b = 14.3240(12) A?, c = 15.3693(13) A?, α = 90.00, β = 94.8190(10),. = 90.00, V = 7820.16 A?3 and Z = 8 at 296(2) K. As indicated by crystal packing, the molecular conjugation planes arrange along the c axis to form micropores due to the hydrogen bonds. In addition, the fluorescent spectrum and luminescence lifetime were studied for 6.