4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester

Base Information

• Chemical Name: 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester
• CAS No.: 151384-79-1
• Molecular Formula: C₁₉H₂₀O₃S
• Molecular Weight: 328.432
• Mol file: 151384-79-1.mol

Synonyms:4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester

Chemical Property of 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester

There total 4 articles about 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

thiophenol (108-98-5) + ethyl 2-methylene-4-oxo-4-phenylbutanoate (108349-24-2) → 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester (151384-79-1)

Guidance literature:

With sodium ethanolate; In ethanol; for 4h;

Reference yield:

ethyl 4-hydroxy-2-methylene-4-phenylbutanoate (109907-81-5,98061-48-4) → 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester (151384-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: PCC / CH₂Cl₂ / 5 h

2: 83 percent / C₂H₅ONa / ethanol / 4 h

With sodium ethanolate; pyridinium chlorochromate; In ethanol; dichloromethane;

Reference yield:

benzaldehyde (100-52-7) → 4-Oxo-4-phenyl-2-phenylsulfanylmethyl-butyric acid ethyl ester (151384-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1: Zn, NH₄Cl / tetrahydrofuran / 60 °C

2: PCC / CH₂Cl₂ / 5 h

3: 83 percent / C₂H₅ONa / ethanol / 4 h

With sodium ethanolate; ammonium chloride; pyridinium chlorochromate; zinc; In tetrahydrofuran; ethanol; dichloromethane;

upstream raw materials:

thiophenol

ethyl 2-methylene-4-oxo-4-phenylbutanoate

ethyl 4-hydroxy-2-methylene-4-phenylbutanoate

benzaldehyde

Downstream raw materials:

2-Formyl-4-oxo-4-phenyl-butyric acid ethyl ester

ethyl 2-phenylfuran-4-carboxylate