2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate

Base Information

• Chemical Name: 2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate
• CAS No.: 1070895-16-7
• Molecular Formula: C₂₃H₃₇NO₆Si
• Molecular Weight: 451.635
• Mol file: 1070895-16-7.mol

Synonyms:2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate

Chemical Property of 2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate

There total 1 articles about 2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-amino-2-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenethyl)-1,3-propanediol (1130205-77-4) + acetic anhydride (108-24-7) → 2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate (1070895-16-7)

Guidance literature:

With dmap; triethylamine; In tetrahydrofuran; at 20 ℃; for 0.25h;

DOI:10.1016/j.bmc.2008.07.003

Reference yield: 98.0%

2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenyl)butyl acetate (1070895-16-7) → 2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-hydroxyphenyl)butyl acetate (162360-77-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.333333h;

DOI:10.1016/j.bmc.2008.07.003

upstream raw materials:

2-amino-2-(4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenethyl)-1,3-propanediol

acetic anhydride

Downstream raw materials:

2-(acetylamino)-2-[(acetyloxy)methyl]-4-(4-hydroxyphenyl)butyl acetate