Technology Process of Cyclopentanecarboxylic acid, 2-oxo-, methyl ester, (1S)- (9CI)
There total 26 articles about Cyclopentanecarboxylic acid, 2-oxo-, methyl ester, (1S)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbonic acid dimethyl ester;
With
sodium hydride;
In
toluene; mineral oil;
for 1h;
Reflux;
cyclopentanone;
In
toluene; mineral oil;
for 3h;
Reflux;
- Guidance literature:
-
With
hydrogenchloride; copper(ll) bromide; lithium diisopropyl amide;
In
tetrahydrofuran; hexane;
1.) -78 deg C, 30 min; -78 deg C, 15 min, 2.) RT;
DOI:10.1021/jo00155a047
- Guidance literature:
-
With
samarium diiodide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
at 0 ℃;
DOI:10.1016/j.tetlet.2006.09.071