N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine

Base Information

Chemical Name:N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine
CAS No.:861648-83-1
Molecular Formula:C₁₀H₁₀Cl₂N₄
Molecular Weight:257.122
Hs Code.:
DSSTox Substance ID:DTXSID901208751

Synonyms:N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine;DTXSID901208751;861648-83-1

Suppliers and Price of N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:256.0282517
Heavy Atom Count:16
Complexity:289

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC1(CN=[N+]=[N-])NC2=CC(=CC(=C2)Cl)Cl

Technology Process of N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine

There total 1 articles about N-[1-(Azidomethyl)cyclopropyl]-3,5-dichlorobenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 861648-82-0
[1-(3,5-dichlorophenylamino)cyclopropyl]methanol

: 861648-83-1
(1-azidomethylcyclopropyl)-(3,5-dichlorophenyl)amine

Guidance literature:: With hydrogen azide; di-isopropyl azodicarboxylate; triphenylphosphine; 2-(3,5-dichlorophenoxy)ethanol; In tetrahydrofuran; benzene; at -78 - 20 ℃; for 22h;
DOI:10.1002/ejoc.200400600

Reference yield: 87.0%

: 861648-83-1
(1-azidomethylcyclopropyl)-(3,5-dichlorophenyl)amine

: (1-aminomethylcyclopropyl)-(3,5-dichlorophenyl)amine dihydrochloride

Guidance literature:: (1-azidomethylcyclopropyl)-(3,5-dichlorophenyl)amine; With 1.3-propanedithiol; triethylamine; In methanol; at 20 ℃; for 24h;

With hydrogenchloride; In diethyl ether; at 0 ℃;
DOI:10.1002/ejoc.200400600

Reference yield:

: 861648-83-1
(1-azidomethylcyclopropyl)-(3,5-dichlorophenyl)amine

: 861648-76-2
4-(3,5-dichlorophenyl)-4,6-diazaspiro[2.4]heptan-5-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: NEt₃; 1,3-propanedithiol / methanol / 24 h / 20 °C

1.2: 87 percent / HCl / diethyl ether / 0 °C

2.1: aq. NaOH

2.2: 44 percent / DMAP / CH₂Cl₂ / 0.5 h / 20 °C

With 1.3-propanedithiol; sodium hydroxide; triethylamine; In methanol;
DOI:10.1002/ejoc.200400600