(1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol

Base Information

Chemical Name:(1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol
CAS No.:861648-82-0
Molecular Formula:C10H11Cl2NO
Molecular Weight:232.109
Hs Code.:2922199090
Mol file:861648-82-0.mol

Synonyms:(1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol

Suppliers and Price of (1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(1-((3,5-Dichlorophenyl)amino)cyclopropyl)methanol 95+%
1g
$ 698.00

Chemenu
(1-((3,5-dichlorophenyl)amino)cyclopropyl)methanol 95%
1g
$ 659.00

Alichem
(1-((3,5-Dichlorophenyl)amino)cyclopropyl)methanol
1g
$ 568.00

Total 3 raw suppliers

Chemical Property of (1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol

Chemical Property:

Boiling Point:385.6±22.0 °C(Predicted)
PKA:15.10±0.10(Predicted)
PSA：32.26000
Density:1.459±0.06 g/cm3(Predicted)
LogP:3.00320

Purity/Quality:

98% ^*data from raw suppliers

(1-((3,5-Dichlorophenyl)amino)cyclopropyl)methanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol

There total 1 articles about (1-((3,5-Dichlorophenyl)aMino)cyclopropyl)Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3032-81-3
3,5-dichloroiodobenzene

: 107-21-1
ethylene glycol

: 115652-52-3
1-amino-1-(hydroxymethyl)cyclopropane hydrochloride

: 861648-82-0
[1-(3,5-dichlorophenylamino)cyclopropyl]methanol

: 2-(3,5-dichlorophenoxy)ethanol

Guidance literature:: 1-amino-1-(hydroxymethyl)cyclopropane hydrochloride; With sodium isopropylate; In isopropyl alcohol; at 20 ℃; for 0.25h;

3,5-dichloroiodobenzene; ethylene glycol; With potassium phosphate; copper(l) iodide; In isopropyl alcohol; at 80 ℃; for 22h; Title compound not separated from byproducts;
DOI:10.1002/ejoc.200400600

Reference yield: 79.0%

: 861648-82-0
[1-(3,5-dichlorophenylamino)cyclopropyl]methanol

: 861648-83-1
(1-azidomethylcyclopropyl)-(3,5-dichlorophenyl)amine

Guidance literature:: With hydrogen azide; di-isopropyl azodicarboxylate; triphenylphosphine; 2-(3,5-dichlorophenoxy)ethanol; In tetrahydrofuran; benzene; at -78 - 20 ℃; for 22h;
DOI:10.1002/ejoc.200400600

Reference yield:

: 861648-82-0
[1-(3,5-dichlorophenylamino)cyclopropyl]methanol

: 861648-76-2
4-(3,5-dichlorophenyl)-4,6-diazaspiro[2.4]heptan-5-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: 79 percent / hydrazoic acid; DIAD; PPh₃ / 2-(3,5-dichlorophenoxy)ethanol / tetrahydrofuran; benzene / 22 h / -78 - 20 °C

2.1: NEt₃; 1,3-propanedithiol / methanol / 24 h / 20 °C

2.2: 87 percent / HCl / diethyl ether / 0 °C

3.1: aq. NaOH

3.2: 44 percent / DMAP / CH₂Cl₂ / 0.5 h / 20 °C

With 1.3-propanedithiol; sodium hydroxide; hydrogen azide; di-isopropyl azodicarboxylate; triethylamine; triphenylphosphine; 2-(3,5-dichlorophenoxy)ethanol; In tetrahydrofuran; methanol; benzene; 1.1: Mitsunobu reaction;
DOI:10.1002/ejoc.200400600