2,6-dideuteriotoluene

Base Information

• Chemical Name: 2,6-dideuteriotoluene
• CAS No.: 80515-60-2
• Molecular Formula: C₇H₈
• Molecular Weight: 94.1246
• Mol file: 80515-60-2.mol

Synonyms:2,6-dideuteriotoluene

Chemical Property of 2,6-dideuteriotoluene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2,6-dideuteriotoluene

There total 5 articles about 2,6-dideuteriotoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2,6-dibromotoluene (69321-60-4) → 2,6-dideuteriotoluene (80515-60-2)

Guidance literature:

With lithium aluminium deuteride; In diethyl ether; at 80 ℃;

DOI:10.1002/jms.1089

Reference yield:

2,6-dideuterio-4-aminotoluene (80515-68-0) → 2,6-dideuteriotoluene (80515-60-2)

Guidance literature:

With hypophosphoric acid; copper(l) chloride;

DOI:10.1016/S0040-4039(00)98745-8

Reference yield:

1-methyl-4-nitrobenzene (99-99-0) → 2,6-dideuteriotoluene (80515-60-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / D₂SO₄ / 85 - 90 °C

2: 68 percent / tin, 38percent HCl / 0.5 h / 75 °C

3: 1.) conc. HCl, H₂O, NaNO₂, 2.) 50percent H₃PO₄ / 1.) 5-8 deg C, 0.5 h, 2.) 5 deg C, 24 h

With hydrogenchloride; tin; phosphoric acid; water; sulfuric acid-d2; sodium nitrite;

DOI:10.1021/jo00346a020

upstream raw materials:

2,6-dideuterio-4-aminotoluene

2,6-dibromotoluene

1-methyl-4-nitrobenzene

2,6-dideuterio-4-nitrotoluene

Downstream raw materials:

[2,6-2H₂]benzyl bromide

2,6-dideuteriobenzyl chloride