69321-60-4

Basic information

• Product Name: 2,6-Dibromotoluene
• Synonyms: 1,3-Dibromo-2-methylbenzene;Benzene, 1,3-dibromo-2-methyl-;2,6-DIBROMOTOLUENE;2,6-Dibromotoluene, 98+%;2,6-Dibromotoluene, 98.5%
• CAS NO: 69321-60-4
• Molecular Formula: C₇H₆Br₂
• Molecular Weight: 249.93
• EINECS: 250-689-9
• Product Categories: Halogen toluene;Bromine Compounds
• Mol File: 69321-60-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 2-6°C
• Boiling Point: 112-113°C 7mm
• Flash Point: 112-113°C/7mm
• Appearance: /
• Density: 1,812 g/cm3
• Vapor Pressure: 0.0436mmHg at 25°C
• Refractive Index: 1.6060
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 3235502
• CAS DataBase Reference: 2,6-Dibromotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dibromotoluene(69321-60-4)
• EPA Substance Registry System: 2,6-Dibromotoluene(69321-60-4)

Safety Data

• Statements: 36/37/38-36/38
• Safety Statements: 26-36/37/39-37
• Hazardous Substances Data: 69321-60-4(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Preparation

2,6-Dibromotoluene is an important pharmaceutical intermediate，It can be made from toluene using sulfonation and desulfonation as intermediate steps in the synthesis.

InChI:InChI=1/C7H6Br2/c1-5-6(8)3-2-4-7(5)9/h2-4H,1H3

Upstream product

• 55289-36-6 3-bromo-2-methylaniline 
• 13194-73-5 3,5-dibromo-4-methylaniline 
• 108545-81-9 1,3-dibromo-5-tert-butyl-2-methylbenzene 
• 1177558-44-9 (3,5-dibromo-4-methylphenyl)amine hydrochloride 
• 594-27-4 tetramethylstannane 
• 827-32-7 4-bromo-5-methyl-2-nitrophenylamine 
• 90914-81-1 4-bromo-3-methylacetanilide 
• 98840-42-7 2,6-diamino-4-t-butyltoluene 
• 4162-89-4 4-(tert-butyl)-2,6-dinitrotoluene 
• 98-51-1 4-tert-butyltoluene 
• 55289-35-5 2-bromo-6-nitrotoluene 
• 101581-06-0 1,3-dibromo-2-methyl-5-nitrobenzene 
• 99-99-0 1-methyl-4-nitrobenzene 
• 80948-78-3 2,4-dibromo-3-methylaniline 

Downstream Products

• 245765-58-6 3-bromo-N-cyclopropyl-2-methyl-aniline 
• 52780-15-1 3'-bromo-2'-methylbenzonitrile 
• 179896-40-3 6-(3-Bromo-2-methylphenyl)-1,2-dihydro-2,2,4-trimethylquinoline 
• 67197-53-9 2-(2,6-dibromophenyl)acetonitrile 
• 1020180-07-7 1-(3-bromo-2-methylphenyl)pyrrolidine 
• 1020180-10-2 1-(3-bromo-2-methylphenyl)piperidine 
• 1020179-99-0 N-(3-bromo-2-methylphenyl)morpholine 
• 1020180-00-0 4,4'-(2-methyl-1,3-phenylene)dimorpholine 
• 1020180-12-4 4-(3-bromo-2-methylphenyl)thiomorpholine 
• 1020180-13-5 cis-4-(3-bromo-2-methylphenyl)-2,6-dimethylmorpholine 
• 1020180-11-3 tert-butyl 4-(3-bromo-2-methylphenyl)piperazine-1-carboxylate 
• 1345093-62-0 C₁₉H₁₃BrS 
• 1353655-99-8 2,6-bis(diisopropylphosphino)toluene 
• 1380403-76-8 4-(2,6-dibromophenyl)-2-methylbutanal 

Relevant articles and documents

Through space interaction between ferrocenes mediated by a thioether

A series of conformationally constrained 2,6-bisferrocenylphenyl thioethers were synthesized via Suzuki-Miyaura cross coupling reactions. Structural information was obtained using X-ray crystallography and dynamic 1H NMR spectroscopic studies,

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The present invention is directed to novel compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use as dual chromaphores having inhibitory activity against PDE4 and muscarinic acetylcholine receptors (mAChRs), and thus being useful for treating respiratory diseases.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention relates to novel compounds of Formula (I) and their use in the treatment of respiratory diseases, including anti-inflammatory and allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.