5-Morpholin-4-YL-nicotinic acid

Base Information

Chemical Name:5-Morpholin-4-YL-nicotinic acid
CAS No.:263270-06-0
Molecular Formula:C10H12 N2 O3
Molecular Weight:208.217
Hs Code.:
European Community (EC) Number:826-744-3
DSSTox Substance ID:DTXSID10406236
Wikidata:Q82211133
Mol file:263270-06-0.mol

Synonyms:5-MORPHOLIN-4-YL-NICOTINIC ACID;263270-06-0;5-morpholinonicotinic acid;5-(morpholin-4-yl)pyridine-3-carboxylic acid;5-morpholin-4-ylpyridine-3-carboxylic Acid;5-Morpholinonicotinicacid;SCHEMBL686827;5-Morpholin-4-yl-nicotinicacid;DTXSID10406236;MFCD04115213;AKOS002664476;AB19702;BB 0260543;CS-0308300;FT-0762297;3-Pyridinecarboxylic acid, 5-(4-morpholinyl)-;EN300-114373;Y13658;A818384;J-517842;F8881-3858;Z1341390434

Suppliers and Price of 5-Morpholin-4-YL-nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Morpholin-4-yl-nicotinic acid
25mg
$ 337.00

TRC
5-Morpholin-4-yl-nicotinicAcid
100mg
$ 90.00

TRC
5-Morpholin-4-yl-nicotinicAcid
50mg
$ 65.00

J&W Pharmlab
5-Morpholin-4-yl-nicotinicacid 96%
250mg
$ 137.00

Crysdot
5-Morpholinonicotinicacid 97%
5g
$ 2632.00

Crysdot
5-Morpholinonicotinicacid 97%
1g
$ 672.00

Chemenu
5-Morpholin-4-yl-nicotinicacid 97%
1g
$ 635.00

American Custom Chemicals Corporation
5-MORPHOLIN-4-YL-NICOTINIC ACID 98.00%
5MG
$ 503.77

AK Scientific
5-Morpholin-4-yl-nicotinicacid
5g
$ 2915.00

Total 15 raw suppliers

Chemical Property of 5-Morpholin-4-YL-nicotinic acid

Chemical Property:

PSA：62.66000
LogP:0.68140
Storage Temp.:2-8°C
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:208.08479225
Heavy Atom Count:15
Complexity:229

Purity/Quality:

98% ^*data from raw suppliers

5-Morpholin-4-yl-nicotinic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=CN=CC(=C2)C(=O)O

Technology Process of 5-Morpholin-4-YL-nicotinic acid

There total 3 articles about 5-Morpholin-4-YL-nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 500865-54-3
methyl 5-morpholin-4-yl-nicotinate

: 263270-06-0
5-(morpholin-1-yl)nicotinic acid

Guidance literature:: methyl 5-morpholin-4-yl-nicotinate; With water; sodium hydroxide; In methanol; at 25 - 65 ℃;

With acetic acid; In water; pH=3;

Reference yield:

: 29681-44-5
5-bromo-3-pyridine carboxylic acid methyl ester

: 263270-06-0
5-(morpholin-1-yl)nicotinic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: caesium carbonate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 25 - 80 °C / Inert atmosphere

2.1: water; sodium hydroxide / methanol / 25 - 65 °C

2.2: pH 3

With water; caesium carbonate; sodium hydroxide; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In methanol; toluene;