[3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Base Information

Chemical Name:[3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester
CAS No.:1025943-55-8
Molecular Formula:C₂₇H₂₃N₃O₅
Molecular Weight:469.497
Hs Code.:

Synonyms:[3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Suppliers and Price of [3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

There total 8 articles about [3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 193006-24-5
3-(3-cyanophenyl)-5-(carbomethoxymethyl)isoxazoline-5-carboxylic acid

: 1025943-55-8
[3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / acetonitrile / 1 h / Heating

2: Et₃N / tetrahydrofuran / Ambient temperature

With thionyl chloride; triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm980405i

Reference yield:

: 7338-27-4
4-methoxy-2-methylene-4-oxobutanoic acid

: 1025943-55-8
[3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / aq. bleach / tetrahydrofuran / 12 h / Ambient temperature

2: SOCl₂ / acetonitrile / 1 h / Heating

3: Et₃N / tetrahydrofuran / Ambient temperature

With sodium hypochlorite; thionyl chloride; triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm980405i

Reference yield:

: 64847-76-3
3-(hydroxyimino)methylbenzonitrile

: 1025943-55-8
[3-(3-cyano-phenyl)-5-(2'-methoxy-biphenyl-4-ylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / aq. bleach / tetrahydrofuran / 12 h / Ambient temperature

2: SOCl₂ / acetonitrile / 1 h / Heating

3: Et₃N / tetrahydrofuran / Ambient temperature

With sodium hypochlorite; thionyl chloride; triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm980405i