1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol

Base Information

• Chemical Name: 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol
• CAS No.: 106484-84-8
• Molecular Formula: C₂₇H₄₀O₄
• Molecular Weight: 428.612
• Mol file: 106484-84-8.mol

Synonyms:1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol

Chemical Property of 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol

There total 7 articles about 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

1-methoxy-2-(methoxymethoxy)benzene (73220-26-5) + phenyl-laurylaldehyde (106484-83-7) → 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol (106484-84-8)

Guidance literature:

With n-butyllithium; In diethyl ether; at 30 ℃; for 0.5h;

DOI:10.1039/c39860001234

Reference yield:

1,12-dodecandiol (5675-51-4) → 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol (106484-84-8)

Guidance literature:

Multi-step reaction with 7 steps

1: p-MeC₆H₄SO₃H / CH₂Cl₂

2: (COCl)2, DMSO, Et₃N / CH₂Cl₂

3: diethyl ether

4: Et₃SiH, CF₃COOH

5: NaOH / methanol

6: 87 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂

7: 49 percent / n-BuLi / diethyl ether / 0.5 h / 30 °C

With triethylsilane; sodium hydroxide; n-butyllithium; oxalyl dichloride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane;

DOI:10.1039/c39860001234

Reference yield:

12-phenyl-1-dodecanol (88336-80-5) → 1-(3-Methoxy-2-methoxymethoxy-phenyl)-12-phenyl-dodecan-1-ol (106484-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂

2: 49 percent / n-BuLi / diethyl ether / 0.5 h / 30 °C

With n-butyllithium; oxalyl dichloride; dimethyl sulfoxide; triethylamine; In diethyl ether; dichloromethane;

DOI:10.1039/c39860001234

upstream raw materials:

1-methoxy-2-(methoxymethoxy)benzene

phenyl-laurylaldehyde

1,12-dodecandiol

12-phenyl-1-dodecanol

Downstream raw materials:

3-(12'-phenyldodecyl)benzene-1,2-diol

2-Methoxy-6-(12-phenyl-dodecyl)-phenol