106484-83-7Relevant articles and documents
2-Oxoamide inhibitors of cytosolic group IVA phospholipase A2with reduced lipophilicity
Antonopoulou, Georgia,Magrioti, Victoria,Kokotou, Maroula G.,Nikolaou, Aikaterini,Barbayianni, Efrosini,Mouchlis, Varnavas D.,Dennis, Edward A.,Kokotos, George
, p. 4544 - 4554 (2016)
Cytosolic GIVA phospholipase A2(GIVA cPLA2) initiates the eicosanoid pathway of inflammation and thus inhibitors of this enzyme constitute novel potential agents for the treatment of inflammatory diseases. Traditionally, GIVA cPLAsu