(2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Base Information

Chemical Name:(2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal
CAS No.:908290-24-4
Molecular Formula:C₁₉H₂₇NO₃
Molecular Weight:317.428
Hs Code.:

Synonyms:(2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Suppliers and Price of (2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

There total 4 articles about (2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 908290-20-0
C₁₉H₂₅NO₃

: 908290-23-3
(2S,3aR,7aR)-1-benzyl-2-[(1'S)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

: 908290-24-4
(2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Guidance literature:: With sodium tetrahydroborate; In methanol; at -20 ℃; for 6h;
DOI:10.1021/jo060592p

Reference yield:

: 908290-16-4
methyl (2S,3aR,7aR)-1-benzyl-6-oxooctahydroindole-2-carboxylate ethylene acetal

: 908290-24-4
(2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 0.5 h

1.2: i-PrMgCl / tetrahydrofuran / 0.67 h / cooling

2.1: tetrahydrofuran; diethyl ether / 1 h / 0 °C

3.1: 365 mg / NaBH₄ / methanol / 6 h / -20 °C

With sodium tetrahydroborate; In tetrahydrofuran; methanol; diethyl ether;
DOI:10.1021/jo060592p

Reference yield:

: C₂₀H₂₈N₂O₄

: 908290-24-4
(2S,3aR,7aR)-1-benzyl-2-[(1'R)-1-hydroxyethyl]octahydroindol-6-one ethylene acetal

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 1 h / 0 °C

2: 365 mg / NaBH₄ / methanol / 6 h / -20 °C

With sodium tetrahydroborate; In tetrahydrofuran; methanol; diethyl ether;
DOI:10.1021/jo060592p