C₁₁H₁₈O₂

Base Information

• Chemical Name: C₁₁H₁₈O₂
• CAS No.: 1010827-59-4
• Molecular Formula: C₁₁H₁₈O₂
• Molecular Weight: 182.263
• Mol file: 1010827-59-4.mol

Synonyms:C₁₁H₁₈O₂

Chemical Property of C₁₁H₁₈O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₈O₂

There total 2 articles about C₁₁H₁₈O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(S)-1-cyclohexylbut-3-en-1-ol (69036-26-6,85029-11-4,94340-22-4,106756-93-8) + crotonaldehyde (123-73-9,4170-30-3) → C11H18O2 (1010827-59-4)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; In dichloromethane; for 6h; Inert atmosphere; Reflux;

DOI:10.1002/anie.201209863

Reference yield:

cyclohexanecarbaldehyde (2043-61-0) → C11H18O2 (1010827-59-4)

Guidance literature:

Multi-step reaction with 2 steps

1: (S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine); 3-nitrobenzoic acid; caesium carbonate; bis(1,5-cyclooctadiene)diiridium(I) dichloride; isopropyl alcohol / tetrahydrofuran / 20 h / 120 °C / Inert atmosphere

2: Hoveyda-Grubbs catalyst second generation / dichloromethane / 6 h / Inert atmosphere; Reflux

With (S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine); bis(1,5-cyclooctadiene)diiridium(I) dichloride; Hoveyda-Grubbs catalyst second generation; caesium carbonate; isopropyl alcohol; 3-nitrobenzoic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1002/anie.201209863

Reference yield: 71.0%

C11H18O2 (1010827-59-4) → (S,E)-5-cyclohexylpent-2-ene-1,5-diol

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; Inert atmosphere;

DOI:10.1002/anie.201209863

upstream raw materials:

(S)-1-cyclohexylbut-3-en-1-ol

crotonaldehyde

cyclohexanecarbaldehyde