diethyl 5-oxo-n-hexylphosphonate

Base Information

• Chemical Name: diethyl 5-oxo-n-hexylphosphonate
• CAS No.: 1068-04-8
• Molecular Formula: C₁₀H₂₁O₄P
• Molecular Weight: 236.248
• Mol file: 1068-04-8.mol

Synonyms:diethyl 5-oxo-n-hexylphosphonate

Chemical Property of diethyl 5-oxo-n-hexylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of diethyl 5-oxo-n-hexylphosphonate

There total 2 articles about diethyl 5-oxo-n-hexylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

methyl vinyl ketone (78-94-4,25038-87-3) + diethyl (2-iodoethyl)phosphonate (142778-06-1) → ethylphosphonic acid diethyl ester (78-38-6) + diethyl 5-oxo-n-hexylphosphonate (1068-04-8)

Guidance literature:

With sodium tetrahydroborate; triethyl borane; tributyltin chloride; In hexane; toluene; at -78 ℃; Yields of byproduct given;

DOI:10.1016/S0040-4020(97)00405-5

Reference yield: 63.0%

diethyl 2-bromoethylphosphonate (5324-30-1) + methyl vinyl ketone (78-94-4,25038-87-3) → ethylphosphonic acid diethyl ester (78-38-6) + diethyl 5-oxo-n-hexylphosphonate (1068-04-8)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; for 1h; Heating;

DOI:10.1016/0040-4020(96)00820-4

upstream raw materials:

diethyl 2-bromoethylphosphonate

methyl vinyl ketone

diethyl (2-iodoethyl)phosphonate