tert-butyl 4-[3-(hydroxymethyl)phenyl]piperazine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-[3-(hydroxymethyl)phenyl]piperazine-1-carboxylate
CAS No.:261925-88-6
Molecular Formula:C16H24 N2 O3
Molecular Weight:292.378
Hs Code.:2933599090
Mol file:261925-88-6.mol

Synonyms:4-(3-Hydroxymethylphenyl)piperazine-1-carboxylicacid tert-butyl ester

Suppliers and Price of tert-butyl 4-[3-(hydroxymethyl)phenyl]piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(3-HYDROXYMETHYL-PHENYL)PIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 502.88

Total 7 raw suppliers

Chemical Property of tert-butyl 4-[3-(hydroxymethyl)phenyl]piperazine-1-carboxylate

Chemical Property:

Vapor Pressure:5.47E-09mmHg at 25°C
Refractive Index:1.553
Boiling Point:452.8°C at 760 mmHg
Flash Point:227.6°C
PSA：53.01000
Density:1.152g/cm³
LogP:2.23890

Purity/Quality:

>=99.0% ^*data from raw suppliers

1-(3-HYDROXYMETHYL-PHENYL)PIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-[3-(hydroxymethyl)phenyl]piperazine-1-carboxylate

There total 5 articles about tert-butyl 4-[3-(hydroxymethyl)phenyl]piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

: 179003-10-2
tert-butyl 4-(3-(methoxycarbonyl)phenyl)-piperazine-1-carboxylate

: 261925-88-6
tert-butyl 4-(3-(hydroxymethyl)phenyl)piperazine-1-carboxylate

Guidance literature:: With lithium borohydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Cooling with ice;

Reference yield: 90.0%

: 261925-94-4
tert-butyl 4-(3-(ethoxycarbonyl)-phenyl)piperazine-1-carboxylate

: 261925-88-6
tert-butyl 4-(3-(hydroxymethyl)phenyl)piperazine-1-carboxylate

Guidance literature:: tert-butyl 4-(3-(ethoxycarbonyl)-phenyl)piperazine-1-carboxylate; With lithium borohydride; In tetrahydrofuran; at 20 ℃; for 48h;

With ammonium chloride; In tetrahydrofuran; water; Cooling with ice;

Reference yield: 84.0%

: 1257849-25-4
4-(3-formyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

: 261925-88-6
tert-butyl 4-(3-(hydroxymethyl)phenyl)piperazine-1-carboxylate

Guidance literature:: 4-(3-formyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

With sodium hydroxide; water; for 0.333333h;