Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate

Base Information

Chemical Name:Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate
CAS No.:937282-79-6
Molecular Formula:C₁₂H₂₁NO₄S
Molecular Weight:275.369
Hs Code.:
European Community (EC) Number:618-967-8

Synonyms:937282-79-6;Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate;SCHEMBL13393848;Isopropyl3-(1-(methylsulfonyl)piperidin-4-yl)acrylate;propan-2-yl (2E)-3-(1-methanesulfonylpiperidin-4-yl)prop-2-enoate;propan-2-yl (E)-3-(1-methylsulfonylpiperidin-4-yl)prop-2-enoate

Suppliers and Price of Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
(E)-isopropyl3-(1-(methylsulfonyl)piperidin-4-yl)acrylate 95
2.5g
$ 1417.00

Crysdot
Isopropyl3-(1-(methylsulfonyl)piperidin-4-yl)acrylate 97%
1g
$ 528.00

Alichem
Isopropyl3-(1-(methylsulfonyl)piperidin-4-yl)acrylate
1g
$ 590.10

Alichem
Isopropyl3-(1-(methylsulfonyl)piperidin-4-yl)acrylate
250mg
$ 227.25

Total 1 raw suppliers

Chemical Property of Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:275.11912932
Heavy Atom Count:18
Complexity:400

Purity/Quality:: (E)-isopropyl3-(1-(methylsulfonyl)piperidin-4-yl)acrylate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)OC(=O)C=CC1CCN(CC1)S(=O)(=O)C
Isomeric SMILES:CC(C)OC(=O)/C=C/C1CCN(CC1)S(=O)(=O)C

Technology Process of Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate

There total 6 articles about Isopropyl 3-(1-(methylsulfonyl)piperidin-4-yl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 241134-35-0
1-(methylsulfonyl)-4-piperidinecarboxaldehyde

: 601-79-6
isopropylmalonic acid

: 937282-79-6
isopropyl 3-(1-methanesulfonylpiperidin-4-yl)propenoate

Guidance literature:: 1-(methylsulfonyl)-4-piperidinecarboxaldehyde; isopropylmalonic acid; piperidine; In toluene; at 85 - 95 ℃;

With hydrogenchloride; In water; toluene; at 40 - 50 ℃; for 0.25h;

Reference yield: 59.0%

: 241134-35-0
1-(methylsulfonyl)-4-piperidinecarboxaldehyde

: 56766-77-9
i-propyl malonic half ester

: 937282-79-6
isopropyl 3-(1-methanesulfonylpiperidin-4-yl)propenoate

Guidance literature:: With piperidine; In toluene; at 85 - 95 ℃;
DOI:10.1021/op700246g

Reference yield:

: 2033-24-1
cycl-isopropylidene malonate

: 937282-79-6
isopropyl 3-(1-methanesulfonylpiperidin-4-yl)propenoate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene; isopropyl alcohol / 85 - 90 °C

2: piperidine / toluene / 85 - 95 °C

With piperidine; In isopropyl alcohol; toluene;
DOI:10.1021/op700246g