Technology Process of 4-chloro-2-(6,6-dimethyl-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)phenyl acetate
There total 3 articles about 4-chloro-2-(6,6-dimethyl-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)phenyl acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
[bis(acetoxy)iodo]benzene; palladium diacetate;
In
acetonitrile;
at 100 ℃;
for 6h;
regioselective reaction;
Inert atmosphere;
DOI:10.1039/c3ra41312h
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium iodide; cerium(III) chloride heptahydrate; ammonium acetate / isopropyl alcohol / 4 h / Reflux
2: palladium diacetate; [bis(acetoxy)iodo]benzene / acetonitrile / 6 h / 100 °C / Inert atmosphere
With
[bis(acetoxy)iodo]benzene; cerium(III) chloride heptahydrate; ammonium acetate; palladium diacetate; sodium iodide;
In
isopropyl alcohol; acetonitrile;
DOI:10.1039/c3ra41312h
- Guidance literature:
-
Multi-step reaction with 3 steps
1: N,N-dimethyl acetamide; toluene / 7 h / Reflux
2: sodium iodide; cerium(III) chloride heptahydrate; ammonium acetate / isopropyl alcohol / 4 h / Reflux
3: palladium diacetate; [bis(acetoxy)iodo]benzene / acetonitrile / 6 h / 100 °C / Inert atmosphere
With
[bis(acetoxy)iodo]benzene; cerium(III) chloride heptahydrate; ammonium acetate; palladium diacetate; sodium iodide;
In
N,N-dimethyl acetamide; isopropyl alcohol; toluene; acetonitrile;
DOI:10.1039/c3ra41312h
