C₁₄H₁₁⁽²⁾H₂NO₂S

Base Information

• Chemical Name: C₁₄H₁₁⁽²⁾H₂NO₂S
• CAS No.: 1426922-66-8
• Molecular Formula: C₁₄H₁₃NO₂S
• Molecular Weight: 261.313
• Mol file: 1426922-66-8.mol

Synonyms:C₁₄H₁₁⁽²⁾H₂NO₂S

Chemical Property of C₁₄H₁₁⁽²⁾H₂NO₂S

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₁₄H₁₁⁽²⁾H₂NO₂S

There total 4 articles about C₁₄H₁₁⁽²⁾H₂NO₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-(methyl(oxo)(phenyl)-λ6-sulfanylidene)benzamide (54090-90-3) → C14H11(2)H2NO2S (1426922-66-8)

Guidance literature:

With potassium hexafluorophosphate; [RhCl₂(p-cymene)]2; tetradeuterioacetic acid; ammonium peroxydisulfate; In 1,2-dichloro-ethane; at 110 ℃; for 22h; chemoselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.6b03898

Reference yield: 54.0%

4-Octyne (1942-45-6) + N-(methyl(oxo)(phenyl)-λ6-sulfanylidene)benzamide (54090-90-3) → C14H11(2)H2NO2S (1426922-66-8) + C15H18(2)HNO

Guidance literature:

With silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; tetradeuterioacetic acid; In 1,4-dioxane; at 120 ℃; for 6h; Schlenk technique; Glovebox;

DOI:10.1021/acs.orglett.8b02068

Reference yield:

S-methyl-S-phenylsulfoximine (4381-25-3) → C14H11(2)H2NO2S (1426922-66-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 13 h / 0 - 20 °C / Schlenk technique; Inert atmosphere

2: tetradeuterioacetic acid; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; silver hexafluoroantimonate / 1,4-dioxane / 6 h / 120 °C / Schlenk technique; Glovebox

With dmap; silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; tetradeuterioacetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane;

DOI:10.1021/acs.orglett.8b02068

upstream raw materials:

N-(methyl(oxo)(phenyl)-λ⁶-sulfanylidene)benzamide

4-Octyne

S-methyl-S-phenylsulfoximine

benzoic acid