6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane

Base Information

• Chemical Name: 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane
• CAS No.: 945495-86-3
• Molecular Formula: C₃₄H₄₁N₅O₆S₃
• Molecular Weight: 711.927
• Mol file: 945495-86-3.mol

Synonyms:6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane

Chemical Property of 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane

There total 2 articles about 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.4%

2,6-bis-(bromomethyl)pyridine (7703-74-4) + tris[2-(N-tosylaminoethyl)]amine (98846-92-5) → 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane (945495-86-3)

Guidance literature:

With potassium carbonate; In acetonitrile; Reflux; Inert atmosphere;

DOI:10.1016/j.ejmech.2013.01.001

Reference yield:

2,2',2''-triaminotriethylamine (4097-89-6) → 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane (945495-86-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran; water / 25 h

2: potassium carbonate / acetonitrile / 20?h / Reflux; Inert atmosphere

With potassium carbonate; In tetrahydrofuran; water; acetonitrile;

DOI:10.1016/j.ejmech.2013.01.001

Reference yield: 98.0%

2-(3-bromopropyl)isoindole-1,3-dione (5460-29-7) + 6-[2-(p-tolylsulfonylamino)ethyl]-3,6,9-triaza-3, 9-p-tolylsulfonyl-1-(2,6)-pyridinecyclodecaphane (945495-86-3) → C45H50N6O8S3 (1401006-68-5)

Guidance literature:

With potassium carbonate; In acetonitrile;

DOI:10.1021/ja300538s

upstream raw materials:

2,6-bis-(bromomethyl)pyridine

tris[2-(N-tosylaminoethyl)]amine

2,2',2''-triaminotriethylamine

Downstream raw materials:

C₃₇H₄₈N₆O₆S₃

C₄₅H₅₀N₆O₈S₃