2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Base Information

Chemical Name:2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone
CAS No.:1356465-31-0
Molecular Formula:C₂₈H₃₄N₂O₅
Molecular Weight:478.588
Hs Code.:

Synonyms:2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Suppliers and Price of 2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

There total 8 articles about 2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1356465-32-1
3-(4-(((R)-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-3,5-dimethylphenyl)-5-(3-(6-phenyl-1,4-dioxaspiro [4.5 ]decan-6-yl)propyl)-1,2,4-oxadiazole

: 1356465-31-0
2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Guidance literature:: With hydrogenchloride; acetic acid; at 0 ℃; for 1.5h;

Reference yield:

: 1444-65-1
(RS)-2-phenylcyclohexanone

: 1356465-31-0
2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Guidance literature:: Multi-step reaction with 8 steps

1.1: sodium hexamethyldisilazane / 1,2-dimethoxyethane / 0.33 h / Cooling with ice

1.2: 0.33 h / 20 °C

1.3: 2 h / 20 °C

2.1: toluene-4-sulfonic acid / benzene / 16.5 h / Reflux

3.1: sodium periodate / osmium(VIII) oxide / water; tert-butyl alcohol / 3 h

4.1: tetrahydrofuran / 18 h / Reflux

5.1: hydrogen / palladium 10% on activated carbon / methanol / 3.5 h / 1292.9 Torr

6.1: sodium hydroxide; methanol / 4 h / 20 °C

7.1: diisopropyl-carbodiimide / acetonitrile / 1 h / 20 °C

7.2: 18 h / 20 °C

8.1: hydrogenchloride; acetic acid / 1.5 h / 0 °C

With hydrogenchloride; methanol; sodium periodate; hydrogen; sodium hexamethyldisilazane; toluene-4-sulfonic acid; acetic acid; sodium hydroxide; diisopropyl-carbodiimide; osmium(VIII) oxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; water; acetonitrile; tert-butyl alcohol; benzene;

Reference yield:

: 7079-07-4
2-allyl-2-phenylcyclohexan-1-one

: 1356465-31-0
2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone

Guidance literature:: Multi-step reaction with 7 steps

1.1: toluene-4-sulfonic acid / benzene / 16.5 h / Reflux

2.1: sodium periodate / osmium(VIII) oxide / water; tert-butyl alcohol / 3 h

3.1: tetrahydrofuran / 18 h / Reflux

4.1: hydrogen / palladium 10% on activated carbon / methanol / 3.5 h / 1292.9 Torr

5.1: sodium hydroxide; methanol / 4 h / 20 °C

6.1: diisopropyl-carbodiimide / acetonitrile / 1 h / 20 °C

6.2: 18 h / 20 °C

7.1: hydrogenchloride; acetic acid / 1.5 h / 0 °C

With hydrogenchloride; methanol; sodium periodate; hydrogen; toluene-4-sulfonic acid; acetic acid; sodium hydroxide; diisopropyl-carbodiimide; osmium(VIII) oxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; water; acetonitrile; tert-butyl alcohol; benzene;