7079-07-4

Basic information

• Product Name: 2-allyl-2-phenylcyclohexan-1-one
• Synonyms: 2-allyl-2-phenylcyclohexan-1-one
• CAS NO: 7079-07-4
• Molecular Weight: 214.307
• Mol File: 7079-07-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-allyl-2-phenylcyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-allyl-2-phenylcyclohexan-1-one(7079-07-4)
• EPA Substance Registry System: 2-allyl-2-phenylcyclohexan-1-one(7079-07-4)

Safety Data

• Hazardous Substances Data: 7079-07-4(Hazardous Substances Data)

Upstream product

• 1444-65-1 (RS)-2-phenylcyclohexanone 
• 107-05-1 3-chloroprop-1-ene 
• 109-64-8 1,3-dibromo-propane 
• 53723-93-6 2-phenyl-1-(trimethylsiloxy)cyclohex-1-ene 
• 107-18-6 allyl alcohol 
• 591-87-7 Allyl acetate 
• 556-56-9 allyl iodid 
• 106-95-6 allyl bromide 

Downstream Products

• 1356465-11-6 (E)-ethyl 4-(1-phenylcyclohexyl)but-2-enoate 
• 1356465-19-4 1-(4-(5-(3-(2-oxo-1-phenylcyclohexyl)propyl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3 - carboxylic acid 
• 1356465-22-9 2-(6-phenyl-1,4-dioxaspiro[4.5]decan-6-yl)acetaldehyde 
• 1356465-24-1 (E)-methyl 4-(6-phenyl-1,4-dioxaspiro[4.5]decan-6-yl)but-2-enoate 
• 1356465-25-2 methyl 4-(6-phenyl-1,4-dioxaspiro[4.5]decan-6-yl)butanoate 
• 1356465-27-4 4-(6-phenyl-1,4-dioxaspiro[4.5]decan-6-yl)butanoic acid 
• 1356465-29-6 tert-butyl 1-(4-(5-(3-(6-phenyl-1,4-dioxaspiro[4.5]decan-6-yl)propyl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylate 
• 1356465-31-0 2-(3-(3-(4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl)-1,2,4-oxadiazol-5-yl)propyl)-2-phenylcyclohexanone 
• 1356465-32-1 3-(4-(((R)-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-3,5-dimethylphenyl)-5-(3-(6-phenyl-1,4-dioxaspiro [4.5 ]decan-6-yl)propyl)-1,2,4-oxadiazole 
• 1356465-15-0 4-(1-phenylcyclohexyl)butanoic acid 
• 1356465-13-8 1-phenylcyclohexanebutanoic acid ethyl ester 
• 1209465-89-3 6-allyl-6-phenyl-1,4-dioxaspiro[4.5]decane 
• 82493-04-7 2-phenyl-2-(2-propenyl)-6-formylcyclohexanone 
• 108011-19-4 (1-phenyl-cyclohexyl)-acetaldehyde 

Relevant articles and documents

Total syntheses of (+)- and (?)-Crinane via Pd(0)-Catalyzed deacylative allylation

An efficient Pd(0)-catalyzed deacylative allylation (DaA) of enolcarbonates (pro-nucleophile) prepared from 2-arylcyclohexanones sharing acyl functionality at C2-position with readily available allylic alcohols (pro-electrophiles) by employing Pd(0)-catalysis under mild reaction conditions. The methodology can be extended for deacylative benzylations (DaB) of enolcarbonates of 2-arylcyclohexanones. As an application of our methodology, we have shown asymmetric total synthesis of Amaryllidaceae alkaloids, (+)- and (?)-crinane.

Catalytic deacylative alkylations (DaA) of enolcarbonates: Total synthesis of (±)-Crinane

An efficient Pd(0)-catalyzed deacylative allylation (DaA) of enolcarbonates (as pro-nucleophile) of cycloalkanones sharing acyl functionality at C2-position with readily available allylic alcohols (as pro-electrophiles) is disclosed under mild reaction conditions. A wide variety of cycloalkanones with an aromatic ring and allyl group at C-2 position (all-carbon quaternary center) are obtained in good to excellent yields (36 examples). The usefulness of this methodology has been shown by a total synthesis of Amaryllidaceae alkaloid, (±)-crinane from 2-aryl cyclohexanone in 5 steps.

SUBSTITUTED OXADIAZOLE COMPOUNDS AND THEIR USE AS S1P1 AGONISTS

Disclosed are compounds of Formula (I): [PLEASE INSERT CHEMICAL STRUCTURE HERE] or stereoisomers, N-oxides, salts, or prodrugs thereof; wherein: Ring A is phenyl or 5- to 6-membered heteroaryl; (i) R1 and R2 are independently C1-C4 alkyl; or (ii) R1 and R