diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate

Base Information

• Chemical Name: diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate
• CAS No.: 1357009-95-0
• Molecular Formula: C₁₃H₁₉N₄O₅PS
• Molecular Weight: 374.357
• Mol file: 1357009-95-0.mol

Synonyms:diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate

Chemical Property of diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate

There total 3 articles about diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

diethyl 2-bromoethylphosphonate (5324-30-1) + 1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate (1357009-95-0)

Guidance literature:

diethyl 2-bromoethylphosphonate; 1-Phenyl-1H-tetrazole-5-thiol; With tetra-(n-butyl)ammonium iodide; potassium carbonate; In N,N-dimethyl-formamide; for 12h; Inert atmosphere;

With ammonium molybdate; water; dihydrogen peroxide; In ethanol; for 12h; Inert atmosphere;

DOI:10.1021/ol203431e

Reference yield:

diethyl 2-bromoethylphosphonate (5324-30-1) → diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate (1357009-95-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide

2: ammonium molybdate; dihydrogen peroxide / ethanol

With ammonium molybdate; dihydrogen peroxide; tetra-(n-butyl)ammonium iodide; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1039/c4ob01910e

Reference yield:

C13H19N4O3PS → diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate (1357009-95-0)

Guidance literature:

With ammonium molybdate; dihydrogen peroxide; In ethanol;

DOI:10.1039/c4ob01910e

upstream raw materials:

diethyl 2-bromoethylphosphonate

1-Phenyl-1H-tetrazole-5-thiol

Downstream raw materials:

diethyl <(2E,4E)-5-phenylpenta-2,4-dienyl>phosphonate

diethyl [(2Z,4E)-5-phenylpenta-2,4-dien-1-yl]phosphonate

diethyl [(E)-5-phenylpent-2-en-1-yl]phosphonate

diethyl [(E)-3-cyclohexylallyl]phosphonate