tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane

Base Information

• Chemical Name: tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane
• CAS No.: 1393109-65-3
• Molecular Formula: C₁₇H₃₀O₂Si
• Molecular Weight: 294.51
• Mol file: 1393109-65-3.mol

Synonyms:tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane

Chemical Property of tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane

There total 1 articles about tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(+/-)-2-methyl-3-(p-methoxyphenyl)propanol (64506-21-4) + tert-butyldimethylsilyl chloride (18162-48-6) → tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane (1393109-65-3)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1021/ja3066682

Reference yield:

tert-butyl-[3-(4-methoxyphenyl)-2-methylpropoxy]dimethylsilane (1393109-65-3) + 2,2,2-trichloroethyl sulfamate (69226-51-3) → 2,2,2-trichloroethyl 3-(tert-butyldimethylsilyloxy)-1-(4-methoxyphenyl)-2-methyl propylsulfamate + 2,2,2-trichloroethyl 3-(tert-butyldimethylsilyloxy)-1-(4-methoxyphenyl)-2-methyl propylsulfamate

Guidance literature:

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; [bis(acetoxy)iodo]benzene; In benzene; at 25 ℃; for 18h; optical yield given as %de; diastereoselective reaction;

DOI:10.1021/ja3066682

upstream raw materials:

(+/-)-2-methyl-3-(p-methoxyphenyl)propanol

tert-butyldimethylsilyl chloride