2-(1-(6-[(2-(P-TOLUOLSULFONYLOXY)ETHYL)(METHYL)AMINO]-2-NAPHTHYL)ETHYLIDENE)MALONITRILE

Base Information

• Chemical Name: 2-(1-(6-[(2-(P-TOLUOLSULFONYLOXY)ETHYL)(METHYL)AMINO]-2-NAPHTHYL)ETHYLIDENE)MALONITRILE
• CAS No.: 259739-02-1
• Molecular Formula: C25H23 N3 O3 S
• Molecular Weight: 445.542
• Mol file: 259739-02-1.mol

Synonyms:Propanedinitrile,[1-[6-[methyl[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]amino]-2-naphthalenyl]ethylidene]-(9CI)

Chemical Property of 2-(1-(6-[(2-(P-TOLUOLSULFONYLOXY)ETHYL)(METHYL)AMINO]-2-NAPHTHYL)ETHYLIDENE)MALONITRILE

Chemical Property:

• PSA: 102.57000
• LogP: 5.89136

Purity/Quality:

98% ^*data from raw suppliers

2-(1-(6-[(2-(PARA-TOLUOLSULFONYLOXY)ETHYL)(METHYL)AMINO]-2-NAPHTHYL)ETHYLIDENE)MALONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(1-(6-[(2-(P-TOLUOLSULFONYLOXY)ETHYL)(METHYL)AMINO]-2-NAPHTHYL)ETHYLIDENE)MALONITRILE

There total 4 articles about 2-(1-(6-[(2-(P-TOLUOLSULFONYLOXY)ETHYL)(METHYL)AMINO]-2-NAPHTHYL)ETHYLIDENE)MALONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

p-toluenesulfonylanhydride (4124-41-8) + 2-(1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethylidene)malononitrile (259739-01-0) → 2-{[6-(2,2-dicyano-1-methylvinyl)-2-naphthyl](methyl)amino}ethyl-4-methylbenzenesulfonate (259739-02-1)

Guidance literature:

With pyridine; at 20 ℃; for 1h;

Reference yield:

1-(6-hydroxy-2-naphthyl)ethan-1-one (10441-41-5) → 2-{[6-(2,2-dicyano-1-methylvinyl)-2-naphthyl](methyl)amino}ethyl-4-methylbenzenesulfonate (259739-02-1)

Guidance literature:

1: Bucherer reaction / 2: Condensation / 3: Tosylation;

Reference yield:

1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethan-1-one (259739-00-9) → 2-{[6-(2,2-dicyano-1-methylvinyl)-2-naphthyl](methyl)amino}ethyl-4-methylbenzenesulfonate (259739-02-1)

Guidance literature:

1: Condensation / 2: Tosylation;

upstream raw materials:

p-toluenesulfonyl chloride

2-(1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethylidene)malononitrile

1-(6-hydroxy-2-naphthyl)ethan-1-one

1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethan-1-one