Dmean

Base Information

Chemical Name:Dmean
CAS No.:259739-01-0
Molecular Formula:C18H17N3O
Molecular Weight:291.352
Hs Code.:
DSSTox Substance ID:DTXSID701146416
Nikkaji Number:J3.268.541B
Mol file:259739-01-0.mol

Synonyms:DMEAN;259739-01-0;(1-[6-[(2-Hydroxyethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile;(1-{6-[(2-hydroxyethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile;SCHEMBL951329;XNRULZQPCJXTMC-UHFFFAOYSA-N;DTXSID701146416;2-(1,1-dicyanopropen-2-yl)-6-[(2-hydroxyethyl)methylamino]naphthalene

Suppliers and Price of Dmean

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
[1-[6-[(2-HYDROXYETHYL)METHYLAMINO]-2-NAPHTHALENYL]ETHYLIDENE]-PROPANEDINITRILE 95.00%
5MG
$ 503.57

Total 3 raw suppliers

Chemical Property of Dmean

Chemical Property:

PSA：71.05000
LogP:3.08896
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:291.137162174
Heavy Atom Count:22
Complexity:503

Purity/Quality:

95% ^*data from raw suppliers

[1-[6-[(2-HYDROXYETHYL)METHYLAMINO]-2-NAPHTHALENYL]ETHYLIDENE]-PROPANEDINITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=C(C#N)C#N)C1=CC2=C(C=C1)C=C(C=C2)N(C)CCO

Technology Process of Dmean

There total 3 articles about Dmean which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.89%

: 109-77-3
malononitrile

: 259739-00-9
1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethan-1-one

: 259739-01-0
2-(1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethylidene)malononitrile

Guidance literature:: With pyridine; at 110 ℃; for 36h;
DOI:10.1016/j.bmcl.2010.11.096

Reference yield:

: 10441-41-5
1-(6-hydroxy-2-naphthyl)ethan-1-one

: 259739-01-0
2-(1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethylidene)malononitrile

Guidance literature:: 1: Bucherer reaction / 2: Condensation;

Reference yield:

: 3900-45-6
6-methoxy-2-acetylnaphthalene

: 259739-01-0
2-(1-(6-((2-hydroxyethyl)(methyl)amino)naphthalen-2-yl)ethylidene)malononitrile

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen bromide / dichloromethane / 2 h / 90 °C

2: potassium disulphite / water / 48 h / 140 °C / Autoclave

3: pyridine / 36 h / 110 °C

With pyridine; potassium disulphite; hydrogen bromide; In dichloromethane; water;
DOI:10.1016/j.bmcl.2010.11.096