3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate

Base Information

Chemical Name:3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate
CAS No.:1023328-33-7
Molecular Formula:C₂₉H₂₈F₃N₃O₄
Molecular Weight:539.554
Hs Code.:

Synonyms:3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate

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Chemical Property of 3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate

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Technology Process of 3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate

There total 1 articles about 3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1023328-42-8
4-[3-[(S)-3-(tert-butyldimethylsilanyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]-3-fluorophenyl piperazine-1-carboxylate

: 1023328-33-7
3-fluoro-4-{1-(4-fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenyl piperazine-1-carboxylate

Guidance literature:: 4-[3-[(S)-3-(tert-butyldimethylsilanyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]-3-fluorophenyl piperazine-1-carboxylate; With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 16h;

With ammonia; In tetrahydrofuran; methanol; dichloromethane;