7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Base Information

Chemical Name:7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III
CAS No.:259522-67-3
Molecular Formula:C₄₈H₈₀O₁₀Si₃
Molecular Weight:901.414
Hs Code.:

Synonyms:7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Suppliers and Price of 7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

There total 4 articles about 7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 204580-30-3
10-O-deacetyl-2-O-debenzoyl-7,10,13-O-tris(triethylsilyl)baccatin III

: 99-04-7
m-Toluic acid

: 259522-67-3
7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Guidance literature:: With dmap; diisopropyl-carbodiimide; In dichloromethane; at 40 ℃; for 40h;
DOI:10.1021/jm800086e

Reference yield:

: 32981-86-5,172018-16-5
10-deacetylbaccatin III

: 259522-67-3
7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / imidazole / dimethylformamide / 40 h / 20 °C

2: 97 percent / Red-Al / tetrahydrofuran / -10 °C

3: DIC; DMAP / CH₂Cl₂

With 1H-imidazole; dmap; dacarbazine; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1: silylation / 2: debenzoylation / 3: Esterification;
DOI:10.1016/S0960-894X(99)00629-0

Reference yield:

: 994-30-9
triethylsilyl chloride

: 259522-67-3
7,10,13-tris(triethylsilyl)-2-debenzoyl-2-(3-methylbenzoyl)-10-deacetylbaccatin III

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / imidazole / dimethylformamide / 40 h / 20 °C

2: 97 percent / Red-Al / tetrahydrofuran / -10 °C

3: DIC; DMAP / CH₂Cl₂

With 1H-imidazole; dmap; dacarbazine; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1: silylation / 2: debenzoylation / 3: Esterification;
DOI:10.1016/S0960-894X(99)00629-0