4-nitrocinnamyl alcohol

Base Information

• Chemical Name: 4-nitrocinnamyl alcohol
• CAS No.: 35271-56-8
• Molecular Formula: C9H9 N O3
• Molecular Weight: 179.175
• Hs Code.: 2906299090
• Mol file: 35271-56-8.mol

Synonyms:2-Propen-1-ol,3-(4-nitrophenyl)-, (E)-; (E)-3-(4-Nitrophenyl)-2-propenol; (E)-4-Nitrocinnamylalcohol; (E)-p-Nitrocinnamyl alcohol; trans-4-Nitrocinnamyl alcohol;trans-p-Nitrocinnamyl alcohol

Chemical Property of 4-nitrocinnamyl alcohol

Chemical Property:

• Melting Point: 127 °C
• Boiling Point: 325.3±22.0 °C(Predicted)
• PKA: 13.91±0.10(Predicted)
• PSA: 66.05000
• Density: 1.282±0.06 g/cm3(Predicted)
• LogP: 2.12350
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

4-Nitrocinnamyl alcohol 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-nitrocinnamyl alcohol

There total 25 articles about 4-nitrocinnamyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-(4-nitrophenyl)-2-propenal (1734-79-8) → 3-(4-nitrophenyl)propyl-2-en-1-ol (35271-56-8,142917-82-6,1504-63-8)

Guidance literature:

With Hf-based metal organic framework-808; In isopropyl alcohol; at 120 ℃; Inert atmosphere;

DOI:10.1016/j.mcat.2021.111405

Reference yield: 98.0%

3-(4-nitrophenyl)-propenal (49678-08-2) → (E)-4-nitrocinnamyl alcohol (35271-56-8)

Guidance literature:

With sodium formate; N-tosylethylenediamine; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; at 80 ℃; for 0.5h;

DOI:10.1002/anie.200602122

Reference yield: 94.0%

methyl 4-nitrocinnamate (637-57-0,1608-36-2,19310-31-7) → 3-(4-nitrophenyl)propyl-2-en-1-ol (35271-56-8,142917-82-6,1504-63-8)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; toluene; for 0.5h; Inert atmosphere; Cooling;

DOI:10.1021/acs.orglett.0c00915

upstream raw materials:

3-(4-nitrophenyl)-propenal

3-(4-nitrophenyl)-2-propenal

p-nitrocinnamoyl chloride

3-(4-nitrophenyl)prop-2-yn-1-ol

Downstream raw materials:

N-[2-hydroxy-3-methoxy-3-(4-nitro-phenyl)-propyl]-phthalimide

(2RS,3RS)-2,3-epoxy-3-(4-nitro-phenyl)-propan-1-ol

3-(4-nitrophenyl)-2-propenyl chloride

(E)-3-(4-nitrophenyl)prop-2-en-1-yl bromide