C₄₈H₅₉N₃O₁₁

Base Information

• Chemical Name: C₄₈H₅₉N₃O₁₁
• CAS No.: 1330629-88-3
• Molecular Formula: C₄₈H₅₉N₃O₁₁
• Molecular Weight: 854.01
• Mol file: 1330629-88-3.mol

Synonyms:C₄₈H₅₉N₃O₁₁

Chemical Property of C₄₈H₅₉N₃O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₈H₅₉N₃O₁₁

There total 6 articles about C₄₈H₅₉N₃O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

BOC-L-aspartic acid 4-benzyl ester (7536-58-5,98482-77-0) + C32H40N2O6 → C48H59N3O11 (1330629-88-3)

Guidance literature:

BOC-L-aspartic acid 4-benzyl ester; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

C₃₂H₄₀N₂O₆; With 4-methyl-morpholine; In tetrahydrofuran; at 0 - 20 ℃; for 26h; pH=9;

DOI:10.1016/j.carres.2011.04.010

Reference yield:

N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4) → C48H59N3O11 (1330629-88-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: barium hydroxide octahydrate; barium(II) oxide

2.1: hydrogenchloride / tetrahydrofuran; water

3.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3.2: 26 h / 0 - 20 °C / pH 9 / Inert atmosphere

4.1: hydrogenchloride / ethyl acetate / 3 h / 0 °C

5.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

5.2: 26 h / 0 - 20 °C / pH 9

With hydrogenchloride; barium hydroxide octahydrate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; barium(II) oxide; In tetrahydrofuran; water; ethyl acetate;

DOI:10.1016/j.carres.2011.04.010

Reference yield:

benzyl bromide (100-39-0) → C48H59N3O11 (1330629-88-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: barium hydroxide octahydrate; barium(II) oxide

2.1: hydrogenchloride / tetrahydrofuran; water

3.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3.2: 26 h / 0 - 20 °C / pH 9 / Inert atmosphere

4.1: hydrogenchloride / ethyl acetate / 3 h / 0 °C

5.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

5.2: 26 h / 0 - 20 °C / pH 9

With hydrogenchloride; barium hydroxide octahydrate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; barium(II) oxide; In tetrahydrofuran; water; ethyl acetate;

DOI:10.1016/j.carres.2011.04.010

upstream raw materials:

BOC-L-aspartic acid 4-benzyl ester

C₃₇H₄₈N₂O₈

Benzyl 2-N-acetylamino-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoside

N-Acetyl-D-glucosamine

Downstream raw materials:

C₅₀H₆₂N₄O₁₂

C₅₆H₇₃N₉O₁₅