4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

Base Information

Chemical Name:4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester
CAS No.:176850-46-7
Molecular Formula:C₁₈H₂₂O₇
Molecular Weight:350.368
Hs Code.:

Synonyms:4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

Suppliers and Price of 4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

There total 1 articles about 4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1490-24-0
4-oxo-pentanoyl chloride

: (2S,3R,3aR,6R,6aR)-2-Benzyloxy-hexahydro-furo[3,2-b]furan-3,6-diol

: 176850-46-7
4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

Guidance literature:: With pyridine; In chloroform; for 2.5h; Ambient temperature;
DOI:10.1016/S0040-4020(97)10005-9

Reference yield: 92.0%

: 176850-46-7
4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

: 176850-52-5
4-Hydroxy-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

Guidance literature:: With sodium tetrahydroborate; zinc(II) chloride; In tetrahydrofuran;
DOI:10.1016/S0040-4020(97)10005-9

Reference yield:

: 176850-46-7
4-Oxo-pentanoic acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester

: 58917-25-2
(R)-5-methyl-2-oxotetrahydrofuran

Guidance literature:: Multi-step reaction with 3 steps

1: ZnCl₂, NaBH₄ / tetrahydrofuran / 0.17 h / -5 °C

2: 1 M aq. LiOH / tetrahydrofuran

3: 1 M aq. HCl / tetrahydrofuran

With hydrogenchloride; lithium hydroxide; sodium tetrahydroborate; zinc(II) chloride; In tetrahydrofuran;
DOI:10.1039/p19960000593