1490-24-0Relevant articles and documents
An ESIPT-Based Fluorescent Probe for Hydrazine Detection in Aqueous Solution and its Application in Living Cells
Ju, Zhiyu,Li, Dapeng,Zhang, Di,Li, Dandan,Wu, Changzeng,Xu, Zhihong
, p. 679 - 687 (2017)
A new fluorescent probe based on “protection–deprotection” sequence and the excited-state intramolecular proton transfer (ESIPT) effect was designed and synthesized. The probe responds rapidly and high selectively toward hydrazine at room temperature, and exhibits a low detection limit of 0.016?μM (0.512?ppb), which is well below the safety level (10?ppb) as regulated by EPA. Moreover, it can be applied for the imaging of hydrazine in living cells.
Hydrazine-selective chromogenic and fluorogenic probe based on levulinated coumarin
Choi, Myung Gil,Hwang, Jiyoung,Moon, Jung Ok,Sung, Jaeyoung,Chang, Suk-Kyu
, p. 5260 - 5263 (2011)
Chemosignaling of hydrazine by selective deprotection of levulinated coumarin was investigated. In the presence of hydrazine, levulinated coumarin was selectively deprotected, resulting in chromogenic and fluorescent turn-on type signaling. The selective naked-eye detectable signaling of hydrazine was possible in the presence of representative metal ions and common anions in an aqueous environment.
Highly diastereoselective samarium diiodide induced cyclizations of new 3-substituted indole derivatives
Beemelmanns, Christine,Reissig, Hans-Ulrich
, p. 4475 - 4480 (2009)
Herein, we describe the synthesis of new functionalized tricyclic and tetracyclic indole derivatives via samarium diiodide induced ketyl cyclizations. The intermediate samarium organyls were either protonated using different proton sources or alkylated wi
STAT DEGRADERS AND USES THEREOF
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Paragraph 00919; 00920, (2021/09/26)
The present invention provides compounds, compositions thereof, and methods of using the same.
New organic-inorganic LDH composites: Synthesis, characterization and catalytic behavior in the green epoxidation of α, β-unsaturated esters
Candu, Natalia,Paul, Diana,Marcu, Ioan-Cezar,Tudorache, Madalina,Parvulescu, Vasile I.,Coman, Simona M.
, p. 127 - 132 (2017/10/05)
New organic-inorganic based LDH composites have been prepared using different methodologies, ie the ion-exchange method (Org@LDH-exch), the reconstruction (Org@LDH-mem) and the direct intercalation (Org@LDH-inter) method, respectively. Irrespective of the procedure, the –C[dbnd]O group of levulinate moiety was envisaged as a potential active organocatalyst in the epoxidation of trans-methylcinnamate to methyl-phenyl-glycidate. The characterisation of these materials through adsorption-desorption isotherms of nitrogen at ?196 °C, XRD, TG-DTA and DRIFT confirmed a successful intercalation only for Org@LDH-inter. The reactions were carried out via in situ generated dioxiranes using levulinate as active organocatalyst and H2O2/acetonitrile mixture as oxidant. Intercalated levulinate in aminoterephthalate/LDH structure led to conversions up to 25% with a total selectivity to methyl-phenyl-glycidate. Besides this, the heterogeneous organocatalyst behave as a green system: the constitutive levulinic acid represents one of the most important renewable platform molecules, while replacing the Oxone reagent with the more benign hydrogen peroxide and the substitution of an inorganic soluble base with the basic function of the LDH-support afford a more benign system.
PREPARATION OF A SUGAR-DERIVED ESTER, GLYCOL AND POLYMERS THEREFROM
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Paragraph 0027, (2017/05/02)
Methods for preparing 1) a sugar-derived ester, 2) a glycol generated from reduction of the ester, and 3) polymers fabricated from polycondensation of the ester or glycol with various diamines and dicarboxylic acids are described. In particular, the ester is levulinic 5-methyl-2-furfural (LMF), the acylation product of hydroxymethyl-furfural (HMF) and either a levulinyl halide or levulinic acid. Each of the embodiments for the synthesis is highly selective for the product and can be executed under relatively mild reaction conditions.
Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes
Joshi, Shrinivas D.,Kumar, Devendra,Dixit, Sheshagiri R.,Tigadi, Nageshwar,More, Uttam A.,Lherbet, Christian,Aminabhavi, Tejraj M.,Yang, Kap Seung
, p. 21 - 39 (2016/08/19)
Novel pyrrolyl hydrazones and their copper complexes have been synthesized and characterized using analytical and spectral techniques to show the tetrahedral geometry for Cu(II) complexes. Biological activities of hydrazones have been assessed to understand the role of metal ion on their biological activity and the effect of pyrrolyl hydrazones. In?vitro antitubercular activity against Mycobacterium tuberculosis of the metal complexes (13b and 13r) exhibited the highest antitubercular activity that are quite close to rifampicin (0.4?μg/mL), giving a MIC of 0.8?μg/mL. All other compounds showed good activity with the MIC values ranging from 1.6 to 100?μg/mL. A comparative study of inhibition values of the ligands and their complexes showed higher antimicrobial activity of the complexes than the ligands. Some compounds have a good activity against InhA and in particular, compounds 12r, 13b and 13r exhibited more than 60% binding with the enzyme even at 5?μM (exhibited good IC50 upto 2.4?μM). Most of the active molecules have a very less cytotoxicity against the human lung cancer cell-line A549. The docking and 3D-QSAR studies have been carried out to provide some insights into the mechanism of action for this class of compounds.
Chiral Surfactant-Type Catalyst: Enantioselective Reduction of Long-Chain Aliphatic Ketoesters in Water
Lin, Zechao,Li, Jiahong,Huang, Qingfei,Huang, Qiuya,Wang, Qiwei,Tang, Lei,Gong, Deying,Yang, Jun,Zhu, Jin,Deng, Jingen
, p. 4419 - 4429 (2015/05/13)
A series of amphiphilic ligands were designed and synthesized. The rhodium complexes with the ligands were applied to the asymmetric transfer hydrogenation of broad range of long-chained aliphatic ketoesters in neat water. Quantitative conversion and excellent enantioselectivity (up to 99% ee) was observed for α-, β-, γ-, δ- and ε-ketoesters as well as for α- and β-acyloxyketone using chiral surfactant-type catalyst 2. The CH/π interaction and the strong hydrophobic interaction of long aliphatic chains between the catalyst and the substrate in the metallomicelle core played a key role in the catalytic transition state. Synergistic effects between the metal-catalyzed site and the hydrophobic microenvironment of the core in the micelle contributed to high stereoselectivity. (Chemical Equation Presented).
Low volatile reactive malodor counteractives and methods of use thereof
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, (2015/09/28)
The present invention provides a novel compound for counteracting amine-based malodor in consumer, industrial and textile products.
LOW VOLATILE REACTIVE MALODOR COUNTERACTIVES AND METHODS OF USE THEREOF
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Page/Page column, (2013/05/08)
The present invention provides a novel compound for counteracting amine-based malodor in consumer, industrial and textile products.
