methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

Base Information

Chemical Name:methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid
CAS No.:944805-43-0
Molecular Formula:C₁₉H₂₄F₃NO₄
Molecular Weight:387.399
Hs Code.:

Synonyms:methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

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Chemical Property of methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

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Technology Process of methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

There total 2 articles about methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 944805-42-9
(2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

: 18107-18-1
diazomethyl-trimethyl-silane

: 944805-43-0
methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

Guidance literature:: In methanol; hexane; benzene;

Reference yield:

: (E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

: 18107-18-1
diazomethyl-trimethyl-silane

: 944805-43-0
methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

: methyl (2R,3R,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

Guidance literature:: In methanol; hexane; benzene;

Reference yield: 78.0%

: 944805-43-0
methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid

: 944805-41-8
tert-butyl (2S,3S,E)-1-hydroxy-3-(4-(trifluoromethyl)phenyl)hex-4-en-2-ylcarbamate

Guidance literature:: methyl (2S,3S,E)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)hex-4-enoic acid; With lithium borohydride; In diethyl ether; at 0 ℃; for 1h;

In methanol; diethyl ether; for 0.333333h;

With water; ammonium chloride; In methanol; diethyl ether;