Technology Process of C19H22F3N3Si
There total 8 articles about C19H22F3N3Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine;
In
N,N-dimethyl-formamide;
at 100 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / N,N-dimethyl-formamide / 0.17 h / 150 °C / Microwave irradiation
2.1: tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane; water / 0.17 h / 150 °C / Microwave irradiation
3.1: palladium 10% on activated carbon; hydrogen / methanol; isopropyl alcohol / 50 °C / Inert atmosphere
4.1: hydrogen bromide; sodium nitrite / water / 0 - 20 °C
4.2: 0 - 20 °C
5.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine / N,N-dimethyl-formamide / 100 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); palladium 10% on activated carbon; hydrogen bromide; hydrogen; potassium acetate; triethylamine; sodium nitrite;
In
methanol; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; isopropyl alcohol;
2.1: |Suzuki Coupling / 5.1: |Sonogashira Cross-Coupling;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine / methanol; ethanol / 6 h / 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane; water / 0.17 h / 150 °C / Microwave irradiation
3.1: palladium 10% on activated carbon; hydrogen / methanol; isopropyl alcohol / 50 °C / Inert atmosphere
4.1: hydrogen bromide; sodium nitrite / water / 0 - 20 °C
4.2: 0 - 20 °C
5.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine / N,N-dimethyl-formamide / 100 °C / Inert atmosphere
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen bromide; hydrogen; triethylamine; N-ethyl-N,N-diisopropylamine; sodium nitrite;
In
methanol; 1,2-dimethoxyethane; ethanol; water; N,N-dimethyl-formamide; isopropyl alcohol;
2.1: |Suzuki Coupling / 5.1: |Sonogashira Cross-Coupling;