66417-30-9

Basic information

• Product Name: 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE
• Synonyms: 3-BROMO-4-METHYLBENZOTRIFLUORIDE;2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE;5-BROMO-2-METHYLBENZOTRIFLUORIDE, 97+%;2-Bromo-4-(trifluoromethyl)toluene
• CAS NO: 66417-30-9
• Molecular Formula: C₈H₆BrF₃
• Molecular Weight: 239.03
• Mol File: 66417-30-9.mol

Chemical Properties

• Boiling Point: 199.4°C at 760 mmHg
• Flash Point: 84.1°C
• Appearance: /
• Density: 1.538g/cm³
• Vapor Pressure: 0.484mmHg at 25°C
• Refractive Index: 1.474
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE(66417-30-9)
• EPA Substance Registry System: 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE(66417-30-9)

Safety Data

• Hazard Codes: F,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 66417-30-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
In the field of organic chemistry, 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE is utilized as a building block for the creation of other organic compounds, facilitating advancements in chemical research and the production of specialty chemicals.

InChI:InChI=1/C8H6BrF3/c1-5-4-6(8(10,11)12)2-3-7(5)9/h2-4H,1H3

Upstream product

• 6140-17-6 4-methylbenzotrifluoride 
• 455-24-3 4-trifluoromethylbenzoic acid 
• 69902-80-3 2-methyl-5-trifluoromethylphenyldiazoniumfluoborate 
• 7789-45-9 copper(II)bromide 
• 3335-35-1 4-methyl-1-(trichloromethyl)benzene 
• 349-95-1 4-(trifluoromethyl)benzylic alcohol 
• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 1066-35-9 dimethylmonochlorosilane 

Downstream Products

• 121793-13-3 1-methyl-4-trifluoromethyl-2-(2',2'-dichloro-1'-fluorovinyl)benzene 
• 725743-50-0 1-(2-methyl-5-(trifluoromethyl)phenyl)ethan-1-one 
• 657-64-7 2-bromo-1-(bromomethyl)-4-(trifluoromethyl)benzene 
• 66417-45-6 Tris-(2-methyl-5-trifluoromethyl-phenyl)-phosphane 

Relevant articles and documents

OXIDATION RESISTANT INDICATOR MOLECULES

Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced

Pesticidal method using 2-phenylimidazole derivatives

The invention provides a method for the control of arthropod, plant nematode, helminth or protozoan pests using a 2-phenylimidazole derivative of the formula: STR1 wherein R1 represents hydrogen, alkyl (optionally substituted by alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, carboxy or alkoxycarbonyl), R2 and R3, each represents hydrogen, halogen, nitro, carboxy, cyano, alkoxycarbonyl, alkanoyl, or optionally alkyl substituted carbamoyl or sulphamoyl, or amino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl) or a group R, RO, RS, RSO or RSO2 in which R represents alkyl (optionally substituted by halogen), and Ar represents a group of the formula: STR2 wherein R4 and R6 each represents halogen or a group R, RO, RS, RSO or RSO2, and R5, R7 and R8 each represents a substituent as defined for R4 and R6, or represents hydrogen, hydroxy, carboxy, nitro, cyano, amino, alkylamino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl), alkoxycarbonyl or alkanoyl or a pesticidally acceptable salt thereof, with the exclusion of compounds in which R2 and R3 simultaneously represent hydrogen atoms, compositions for use in the method and novel compounds of formula I.

σπ* orthogonal intramolecular charge-transfer (OICT) excited states and photoreaction mechanism of trifluoromethyl-substituted phenyldisilanes

Photophysical and photochemical properties of phenyldisilanes having a trifluoromethyl substituent on a benzene ring as one of the most suitable substituents for stabilization of the OICT (σπ* orthogonal intramolecular charge transfer) state were investig

SYNTHESIS AND POLYMERIZATION OF 2,5-DISUBSTITUTED PHENYLACETYLENES CONTAINING TRIFLUOROMETHYL GROUPS

Four phenylacetylenes (2-R2-5-R5-C6H3CCH : 1a R2=R5=CF3; 1b R2=CF3, R5=CH3; 1c R2=CH3, R5=CF3; 1d R2=R5=CH3) were synthesized via lithio compounds or Grignard reagent.Bromo(methyl)benzotrifluorides, the precursors for the lithio compounds, were prepared by the fluorination of the corresponding benzoic acids with sulfur tetrafluoride.Polymerization using transition metal catalysts provided polyacetylenes in high yields for all the monomers, while the yields of γ-ray induced polymerization depended on the monomers.The molecular weights of polyacetylenes have a positive correlation with the yields for all the polymerizations.The substituent effects on the molecular weights and tehrmal stabilities of polymers obtained were discussed.

Trifluoromethyl substituted 1-aminoindanes

4(5 or 6 or 7)-Trifluoromethyl-1-aminoindanes, useful as inhibitors of N-methyl transferase.

M-Bromo-benzotrifluorides

A process for preparing an m-bromo-benzotrifluoride by brominating an unsubstituted, halo or alkyl substituted benzotrichloride in the presence of a catalyst and thereafter fluorinating the brominated product at elevated temperature and pressure. Also disclosed are new m-bromo-benzotrifluorides including 4-fluoro-3-bromo-benzotrifluoride and 4-methyl-3-bromobenzotrifluoride.