N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

Base Information

• Chemical Name: N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide
• CAS No.: 158098-91-0
• Molecular Formula: C₁₉H₂₇N₃O₂S
• Molecular Weight: 361.508
• Mol file: 158098-91-0.mol

Synonyms:N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

Chemical Property of N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

There total 3 articles about N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

acetyl chloride (75-36-5) + C17H27N3O2S (158098-79-4) → N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide (158098-91-0)

Guidance literature:

for 15h; Heating;

DOI:10.1002/prac.19953370168

Reference yield:

methyl 4-(n-nonyloxy)benzoate (147080-44-2) → N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide (158098-91-0)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂NNH₂*H₂O / ethanol / 8 h / Heating

2: HCl / ethanol / 18 h / Heating

3: Heating

With hydrogenchloride; hydrazine hydrate; In ethanol;

DOI:10.1515/znb-1997-1215

Reference yield:

4-(n-nonyloxy)benzoyl hydrazine (64328-65-0) → N-[5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide (158098-91-0)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / ethanol / 18 h / Heating

2: Heating

With hydrogenchloride; In ethanol;

DOI:10.1515/znb-1997-1215

upstream raw materials:

acetyl chloride

C₁₇H₂₇N₃O₂S

methyl 4-(n-nonyloxy)benzoate

4-(n-nonyloxy)benzoyl hydrazine

Downstream raw materials:

5-(4-Nonyloxy-phenyl)-[1,3,4]thiadiazol-2-ylamine