(-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

Base Information

Chemical Name:(-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane
CAS No.:249622-10-4
Molecular Formula:C₂₁H₂₈N₂O₂
Molecular Weight:340.466
Hs Code.:

Synonyms:(-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

Suppliers and Price of (-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

There total 2 articles about (-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 75-31-0
isopropylamine

: 249622-09-1
(-)-(1R,2R)-2-N,N-dimethylamino-1-ethoxycarbonylmethoxy-1,2-diphenylethane

: 249622-10-4
(-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

Guidance literature:: With sodium methylate; In toluene; at 55 ℃; for 24h;
DOI:10.1016/S0040-4020(99)00644-4

Reference yield:

: 249622-08-0
(1R,2R)-2-(dimethylamino)-1,2-diphenylethanol

: 249622-10-4
(-)-(1R,2R)-2-N,N-dimethylamino-1-isopropylaminocarbonylmethoxy-1,2-diphenylethane

Guidance literature:: Multi-step reaction with 2 steps

1.1: BuLi / dimethylformamide / 1 h / -60 °C

1.2: 42 percent / dimethylformamide / 48 h / -30 °C

2.1: 72 percent / NaOCH₃ / toluene / 24 h / 55 °C

With n-butyllithium; sodium methylate; In N,N-dimethyl-formamide; toluene; 1.1: Metallation / 1.2: Substitution / 2.1: Substitution;
DOI:10.1016/S0040-4020(99)00644-4