tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

Base Information

Chemical Name:tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate
CAS No.:946859-86-5
Molecular Formula:C₁₅H₂₃NO₆S
Molecular Weight:345.417
Hs Code.:

Synonyms:tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

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Technology Process of tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

There total 12 articles about tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: (1R,2R)-2-((tert-butoxycarbonyl)amino)-3-hydroxy-1-(4-(methylsulfonyl)phenyl)propyl acetate

: 946859-86-5
tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

Guidance literature:: With potassium carbonate; In water; at 20 ℃; for 2h; Reagent/catalyst; Solvent; Temperature;

Reference yield:

: (2S,3R)-3-hydroxy-2-(tert-butyloxycarbamoyl)-3-(4-methylsulfonylphenyl)propionic acid ethyl ester

: 946859-86-5
tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃; for 8h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 946859-86-5
tert-butyl N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]carbamate

Guidance literature:: D(-)-treo-1-(p.metilsolfonilfenil)-2-amino-1,3-propandiolo cloridrato; With sodium hydrogencarbonate; In 1,4-dioxane; water;

di-tert-butyl dicarbonate; In 1,4-dioxane; for 48h;