(S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid

Base Information

Chemical Name:(S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid
CAS No.:257288-48-5
Molecular Formula:C₁₇H₁₇NO₂S
Molecular Weight:299.393
Hs Code.:
DSSTox Substance ID:DTXSID801290208
Mol file:257288-48-5.mol

Synonyms:257288-48-5;H-D-Cys(Fm)-OH;(S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid;DTXSID801290208;S-(9-Fluorenylmethyl)-D-Cysteine;FD21331;S-(9H-Fluoren-9-ylmethyl)-D-cysteine;(S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoicacid;(2S)-2-amino-3-{[(9H-fluoren-9-yl)methyl]sulfanyl}propanoic acid

Suppliers and Price of (S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoicacid 97%
5g
$ 698.00

American Custom Chemicals Corporation
S-(9-FLUORENYLMETHYL)-D-CYSTEINE 95.00%
1G
$ 742.00

American Custom Chemicals Corporation
S-(9-FLUORENYLMETHYL)-D-CYSTEINE 95.00%
5MG
$ 502.49

Total 7 raw suppliers

Chemical Property of (S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid

Chemical Property:

Boiling Point:521.5±50.0 °C(Predicted)
PKA:2.06±0.10(Predicted)
PSA：88.62000
Density:1.292±0.06 g/cm3(Predicted)
LogP:3.64430
Storage Temp.:-15°C
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:299.09799996
Heavy Atom Count:21
Complexity:354

Purity/Quality:

99% ^*data from raw suppliers

(S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)CSCC(C(=O)O)N
Isomeric SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)CSC[C@H](C(=O)O)N

Technology Process of (S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid

There total 3 articles about (S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 71532-40-6
(9H-fluoren-9-yl)methyl 4-methylbenzenesulfonaye

: 52-89-1
l-cysteine hydrochloride

: 84888-38-0,257288-48-5
(R)-9H-fluorenyl-9-methyl-L-cysteine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)81481-2

Reference yield: 91.0%

: 52-90-4
L-Cysteine

: 71532-40-6
(9H-fluoren-9-yl)methyl 4-methylbenzenesulfonaye

: 84888-38-0,257288-48-5
(R)-9H-fluorenyl-9-methyl-L-cysteine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1021/ol0488183

Reference yield:

: 24324-17-2
9-Fluorenylmethanol

: 84888-38-0,257288-48-5
(R)-9H-fluorenyl-9-methyl-L-cysteine

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / CHCl₃; pyridine / 6 h / 20 °C

2: 91 percent / DIPEA / dimethylformamide / 24 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In pyridine; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/ol0488183