2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI)

Base Information

Chemical Name:2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI)
CAS No.:256458-27-2
Molecular Formula:C₇H₉NO₃
Molecular Weight:155.153
Hs Code.:
Mol file:256458-27-2.mol

Synonyms:2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI)

Suppliers and Price of 2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
(5R)-5-(acetyloxy)-1,5-dihydro-1-methyl-2H-Pyrrol-2-one 97.00%
25G
$ 5120.00

AccelPharmtech
(5R)-5-(acetyloxy)-1,5-dihydro-1-methyl-2H-Pyrrol-2-one 97.00%
5G
$ 2750.00

AccelPharmtech
(5R)-5-(acetyloxy)-1,5-dihydro-1-methyl-2H-Pyrrol-2-one 97.00%
1G
$ 2370.00

Total 1 raw suppliers

Chemical Property of 2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI)

Chemical Property:

Boiling Point:295.4±40.0 °C(Predicted)
PKA:-3.37±0.40(Predicted)
PSA：46.61000
Density:1.22±0.1 g/cm3(Predicted)
LogP:-0.15830

Purity/Quality:: (5R)-5-(acetyloxy)-1,5-dihydro-1-methyl-2H-Pyrrol-2-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI)

There total 6 articles about 2H-Pyrrol-2-one,5-(acetyloxy)-1,5-dihydro-1-methyl-,(5R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 546-67-8
lead(IV) tetraacetate

: 118486-97-8
1-methyl-2-(tributyltin)pyrrole

: 118487-00-6,175796-23-3,256458-27-2
acetic acid 1-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-yl ester

Guidance literature:: In dichloromethane; for 32h; Heating;
DOI:10.1039/c39880000560

Reference yield:

: 55260-27-0
5-hydroxy-1-methyl-1,5-dihydropyrrol-2-one

: 108-24-7
acetic anhydride

: 175796-23-3,256458-27-2
acetic acid 1-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-yl ester

Guidance literature:: With pyridine; Candida antarctica lipase; Multistep reaction; 2.) n-hexane, n-BuOH;
DOI:10.1021/jo982151e

Reference yield:

: 96-54-8
N-Methylpyrrole

: 118487-00-6,175796-23-3,256458-27-2
acetic acid 1-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: oxygen; Methylene Blue / H₂O / Irradiation

2: 2.46 g / pyridine / 18 h / 20 °C

With pyridine; oxygen; methylene blue; In water; 1: Oxidation / 2: Acetylation;
DOI:10.1021/jo991062e