2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether

Base Information

• Chemical Name: 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether
• CAS No.: 897918-43-3
• Molecular Formula: C₃₆H₃₂O₅
• Molecular Weight: 544.647
• Mol file: 897918-43-3.mol

Synonyms:2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether

Chemical Property of 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether

There total 3 articles about 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-[4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl]ethanol (897918-42-2) + trityl chloride (76-83-5) → 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether (897918-43-3)

Guidance literature:

In pyridine;

DOI:10.1021/jo060501o

Reference yield:

benzyl [4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl]acetate (897918-40-0) → 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether (897918-43-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / H₂ / Pd/C / tetrahydrofuran / 2 h / 20 °C / 2844.31 Torr

2: 100 percent / BH₃ / tetrahydrofuran / 1 h / 20 °C

3: 75 percent / pyridine

With borane; hydrogen; palladium on activated charcoal; In tetrahydrofuran; pyridine;

DOI:10.1021/jo060501o

Reference yield:

[4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl]acetic acid (897918-41-1) → 2-(4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl)ethyl triphenylmethyl ether (897918-43-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / BH₃ / tetrahydrofuran / 1 h / 20 °C

2: 75 percent / pyridine

With borane; In tetrahydrofuran; pyridine;

DOI:10.1021/jo060501o

upstream raw materials:

2-[4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl]ethanol

trityl chloride

[4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl]acetic acid

benzyl [4-acetoxy-2-ethoxycarbonylnaphthalen-1-yl]acetate

Downstream raw materials:

[4-benzyloxy-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl]ethyl triphenylmethyl ether

2-(4-benzyloxy-2-aminonaphthalen-1-yl)ethyl triphenylmethyl ether

2-[4-benzyloxy-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl]ethyl methanesulfonate

[4-benzyloxy-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl]ethyl chloride