Imidazo[1,2-d][1,2,4]triazin-5(6H)-one

Base Information

Chemical Name:Imidazo[1,2-d][1,2,4]triazin-5(6H)-one
CAS No.:256408-48-7
Molecular Formula:C5H4 N4 O
Molecular Weight:136.11146
Hs Code.:
DSSTox Substance ID:DTXSID50473003
Wikidata:Q82302185
Mol file:256408-48-7.mol

Synonyms:256408-48-7;imidazo[1,2-d][1,2,4]triazin-2-one;Imidazo[1,2-d][1,2,4]triazin-5(6H)-one;SCHEMBL7700737;SCHEMBL12861408;DTXSID50473003

Suppliers and Price of Imidazo[1,2-d][1,2,4]triazin-5(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Imidazo[1,2-d][1,2,4]triazin-5(6H)-one

Chemical Property:

PKA:7.20±0.20(Predicted)
PSA：63.31000
Density:1.74±0.1 g/cm3(Predicted)
LogP:-0.17010
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:136.03851076
Heavy Atom Count:10
Complexity:190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C(=N1)C=NNC2=O

Technology Process of Imidazo[1,2-d][1,2,4]triazin-5(6H)-one

There total 1 articles about Imidazo[1,2-d][1,2,4]triazin-5(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: N'-(1H-imidazol-2-ylmethylene)-hydrazinecarboxylic acid ethyl ester

: 256408-48-7
imidazo[1,2-d][1,2,4]triazin-4-one

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 100 ℃; for 10h;
DOI:10.1016/S0040-4020(99)00843-1

Reference yield: 47.0%

: 100-39-0
benzyl bromide

: 256408-48-7
imidazo[1,2-d][1,2,4]triazin-4-one

: 256408-53-4
2-benzylimidazo[1,2-d][1,2,4]triazinium-4-olate

Guidance literature:: With potassium carbonate; In 1,4-dioxane; at 40 ℃; for 10h;
DOI:10.1016/S0040-4020(99)00843-1

Reference yield:

: 256408-48-7
imidazo[1,2-d][1,2,4]triazin-4-one

: 5-benzyl-3-diethylamino-2-methyl-5,6-dihydroimidazo[1,2-d][1,2,4]triazocin-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / K₂CO₃ / dioxane / 10 h / 40 °C

2: 71 percent / benzene / 20 h / 110 °C

With potassium carbonate; In 1,4-dioxane; benzene; 1: Methylation / 2: Cycloaddition;
DOI:10.1016/S0040-4020(99)00843-1